Polymeric nanocarriers of drug delivery systems in cancer therapy

N Avramović, B Mandić, A Savić-Radojević, T Simić - Pharmaceutics, 2020 - mdpi.com
Conventional chemotherapy is the most common therapeutic method for treating cancer by
the application of small toxic molecules thatinteract with DNA and causecell death …

Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy

M Ashrafizadeh, M Delfi, F Hashemi, A Zabolian… - Carbohydrate …, 2021 - Elsevier
Gene therapy is an emerging and promising strategy in cancer therapy where small
interfering RNA (siRNA) system has been deployed for down-regulation of targeted gene …

Polysaccharide-based nanoparticles for theranostic nanomedicine

M Swierczewska, HS Han, K Kim, JH Park… - Advanced drug delivery …, 2016 - Elsevier
Polysaccharides are natural biological molecules that have numerous advantages for
theranostics, the integrated approach of therapeutics and diagnostics. Their derivable …

Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances

NS Gandhi, RK Tekade, MB Chougule - Journal of Controlled Release, 2014 - Elsevier
Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …

Immunostimulatory effect of chitosan and quaternary chitosan: A review of potential vaccine adjuvants

X Li, R Xing, C Xu, S Liu, Y Qin, K Li, H Yu, P Li - Carbohydrate polymers, 2021 - Elsevier
Vaccines have always been the most effective preventive treatment. Advancements in the
field of vaccine is inseparable from adjuvants. Adjuvants are substances added to vaccines …

Advances in self-assembled chitosan nanomaterials for drug delivery

Y Yang, S Wang, Y Wang, X Wang, Q Wang… - Biotechnology …, 2014 - Elsevier
Nanomaterials based on chitosan have emerged as promising carriers of therapeutic agents
for drug delivery due to good biocompatibility, biodegradability, and low toxicity. Chitosan …

Advances in chitosan-based nanoparticles for oncotherapy

E Zhang, R Xing, S Liu, Y Qin, K Li, P Li - Carbohydrate polymers, 2019 - Elsevier
Chitosan has attracted considerable attention as an anti-tumor drug carrier material in recent
years, which is due to its biocompatibility and biodegradability, as well as the simple and …

Oral delivery of RNAi for cancer therapy

H Afrin, R Geetha Bai, R Kumar, SS Ahmad… - Cancer and Metastasis …, 2023 - Springer
Cancer is a major health concern worldwide and is still in a continuous surge of seeking for
effective treatments. Since the discovery of RNAi and their mechanism of action, it has …

Lignin, lipid, protein, hyaluronic acid, starch, cellulose, gum, pectin, alginate and chitosan-based nanomaterials for cancer nanotherapy: Challenges and opportunities

CC Carrion, M Nasrollahzadeh, M Sajjadi… - International Journal of …, 2021 - Elsevier
Although nanotechnology-driven drug delivery systems are relatively new, they are rapidly
evolving since the nanomaterials are deployed as effective means of diagnosis and delivery …

Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics

M Ashrafizadeh, Z Ahmadi, N Mohamadi… - International journal of …, 2020 - Elsevier
Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …