Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

It's Not Easy Being Green: A Narrative Review on the Microbiology, Virulence and Therapeutic Prospects of Multidrug-Resistant Pseudomonas aeruginosa

P Behzadi, Z Baráth, M Gajdács - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is the most frequent cause of infection among non-fermenting
Gram-negative bacteria, predominantly affecting immunocompromised patients, but its …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

MF Moradali, S Ghods, BHA Rehm - Frontiers in cellular and infection …, 2017 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing

J Chadha, K Harjai, S Chhibber - Environmental microbiology, 2022 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …

Cyclic di-GMP: second messenger extraordinaire

U Jenal, A Reinders, C Lori - Nature Reviews Microbiology, 2017 - nature.com
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

M Valentini, A Filloux - Journal of Biological Chemistry, 2016 - ASBMB
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

Pseudomonas aeruginosa : new insights into pathogenesis and host defenses

SL Gellatly, REW Hancock - Pathogens and disease, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Type VI secretion system effectors: poisons with a purpose

AB Russell, SB Peterson, JD Mougous - Nature reviews microbiology, 2014 - nature.com
The type VI secretion system (T6SS) mediates interactions between a broad range of Gram-
negative bacterial species. Recent studies have led to a substantial increase in the number …

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …