Leprosy is a disease caused by Mycobacterium leprae (ML) with diverse clinical
manifestations, which are strongly correlated with the host's immune response. Skin lesions …

Leprosy is a neglected chronic infectious disease caused by obligate intracellular bacilli,
Mycobacterium leprae and Mycobacterium lepromatosis. Despite multidrug therapy (MDT) …

Background Leprosy diagnosis is mainly based on clinical evaluation, although this
approach is difficult, especially for untrained physicians. We conducted a temporary …

Leprosy remains an important health problem in a number of regions. Early detection of
infection, followed by effective treatment, is critical to reduce disease progression. New …

BACKGROUND Leprosy is a chronic infectious disease, still endemic in many countries that
may lead to neurological, ophthalmic, and motor sequelae if not treated early. Access to …

Diagnostic tests for leprosy are limited, especially to identify early leprosy cases. We
performed active case findings of leprosy to validate three potential antigen candidates and …

Although curable, leprosy requires better diagnostic and prognostic tools to accompany
therapeutic strategies. We evaluated the serum samples of leprosy patients from Venezuela …

Leprosy is a debilitating chronic disease caused by infection with Mycobacterium leprae. A
World Health Organization-directed control strategy based upon the identification and …

The present review briefly summarizes the highlights of the recent advances in
Mycobacterium leprae-specific tests for early diagnosis of leprosy. In addition to establishing …

Despite the reduction in the number of leprosy cases registered worldwide as a result of the
widespread use of multidrug therapy, the number of new cases detected each year remains …