Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer
N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …
Ultrasound-responsive droplets for therapy: A review
The last two decades have seen the development of acoustically activated droplets, also
known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through …
known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through …
Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery …
P Mohan, N Rapoport - Molecular pharmaceutics, 2010 - ACS Publications
Doxorubicin (DOX) is one of the most commonly used chemotherapeutic drugs and is a
popular research tool due to the inherent fluorescence of the DOX molecule. After DOX …
popular research tool due to the inherent fluorescence of the DOX molecule. After DOX …
Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound
PS Sheeran, S Luois, PA Dayton, TO Matsunaga - Langmuir, 2011 - ACS Publications
Recent efforts in the area of acoustic droplet vaporization with the objective of designing
extravascular ultrasound contrast agents has led to the development of stabilized, lipid …
extravascular ultrasound contrast agents has led to the development of stabilized, lipid …
Phase-change contrast agents for imaging and therapy
PS Sheeran, PA Dayton - Current pharmaceutical design, 2012 - ingentaconnect.com
Phase-change contrast agents (PCCAs) for ultrasound-based applications have resulted in
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …
Decafluorobutane as a phase-change contrast agent for low-energy extravascular ultrasonic imaging
PS Sheeran, VP Wong, S Luois, RJ McFarland… - Ultrasound in medicine …, 2011 - Elsevier
Currently available microbubbles used for ultrasound imaging and therapeutics are limited
to intravascular space due to their size distribution in the micron range. Phase-change …
to intravascular space due to their size distribution in the micron range. Phase-change …
Acoustic droplet vaporization is initiated by superharmonic focusing
Acoustically sensitive emulsion droplets composed of a liquid perfluorocarbon have the
potential to be a highly efficient system for local drug delivery, embolotherapy, or for tumor …
potential to be a highly efficient system for local drug delivery, embolotherapy, or for tumor …
The role of inertial cavitation in acoustic droplet vaporization
ML Fabiilli, KJ Haworth, NH Fakhri… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
The vaporization of a superheated droplet emulsion into gas bubbles using ultrasound-
termed acoustic droplet vaporization (ADV)-has potential therapeutic applications in …
termed acoustic droplet vaporization (ADV)-has potential therapeutic applications in …
Characterization of submicron phase-change perfluorocarbon droplets for extravascular ultrasound imaging of cancer
Because many tumors possess blood vessels permeable to particles with diameters of 200
nm, it is possible that submicron perfluorocarbon droplets could constitute a novel …
nm, it is possible that submicron perfluorocarbon droplets could constitute a novel …
Delivery of chlorambucil using an acoustically-triggered perfluoropentane emulsion
ML Fabiilli, KJ Haworth, IE Sebastian… - Ultrasound in medicine …, 2010 - Elsevier
Ultrasound-mediated delivery systems have mainly focused on microbubble contrast agents
as carriers of drugs or genetic material. This study uses micron-sized, perfluoropentane …
as carriers of drugs or genetic material. This study uses micron-sized, perfluoropentane …