Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …

Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

The genus Legionella comprises 65 species, among which Legionella pneumophila is a
human pathogen causing severe pneumonia. To understand the evolution of an …

Bacteria of the genus Legionella are natural pathogens of amoebae that can cause a severe
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …

The reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) protects
against redox stress by providing reducing equivalents to antioxidants such as glutathione …

Advances in the field of redox biology have contributed to the understanding of the
complexity of the thiol-based system in mediating signal transduction. The redox …

TrxR is an NADPH-dependent selenoenzyme upregulated in a number of cancers. It plays a
pivotal role in cancer progression and represents an increasingly attractive target for …

Methanethiol is a toxic gas produced through bacterial degradation of sulfur‐containing
amino acids. Applying a novel enzymatic assay, we here identified a methanethiol oxidase …

Organic selenium and tellurium compounds are known for their broad-spectrum effects in a
variety of experimental disease models. However, these compounds commonly display high …

The thiol-based glutathione reductase (GR) and thioredoxin reductase (TrxR) are the major
antioxidant enzymes present in various organisms that maintain the internal redox …