Autophagy in liver diseases: a review
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
[HTML][HTML] The AMPK pathway in fatty liver disease
C Fang, J Pan, N Qu, Y Lei, J Han, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism disorders are the primary causes for the occurrence and progression of
various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty …
various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty …
[HTML][HTML] Cell death in liver diseases: a review
Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …
[HTML][HTML] Alcoholic liver disease: pathogenesis and current management
NA Osna, TM Donohue Jr… - Alcohol research: current …, 2017 - ncbi.nlm.nih.gov
Excessive alcohol consumption is a global healthcare problem. The liver sustains the
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …
[HTML][HTML] Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
Impaired TFEB-mediated lysosome biogenesis and autophagy promote chronic ethanol-induced liver injury and steatosis in mice
Background & Aims Defects in lysosome function and autophagy contribute to the
pathogenesis of alcoholic liver disease. We investigated the mechanisms by which alcohol …
pathogenesis of alcoholic liver disease. We investigated the mechanisms by which alcohol …
Lytic cell death in metabolic liver disease
Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …
Alcoholic liver disease
HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …
[HTML][HTML] Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy
V Subramaniyan, S Chakravarthi, R Jegasothy… - Toxicology reports, 2021 - Elsevier
One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …
[HTML][HTML] Alcohol-related liver disease: basic mechanisms and clinical perspectives
SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …