Plasmodium falciparum pre-erythrocytic stage vaccine development

J Molina-Franky, L Cuy-Chaparro, A Camargo… - Malaria journal, 2020 - Springer
Worldwide strategies between 2010 and 2017 aimed at controlling malarial parasites
(mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence …

Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development

ME Patarroyo, A Bermúdez, MA Patarroyo - Chemical reviews, 2011 - ACS Publications
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …

Recent advances in the development of a chemically synthesised anti-malarial vaccine

H Curtidor, ME Patarroyo… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Obtaining an effective antimalarial vaccine has represented one of the biggest
public health challenges over the last 50 years. Despite efforts by many laboratories around …

Functional, immunological and three-dimensional analysis of chemically synthesised sporozoite peptides as components of a fully-effective antimalarial vaccine

H Curtidor, M Vanegas, MP Alba… - Current medicinal …, 2011 - ingentaconnect.com
Our ongoing search for a fully-effective vaccine against the Plasmodium falciparum parasite
(causing the most lethal form of human malaria) has been focused on identifying and …

Structural analysis of owl monkey MHC-DR shows that fully-protective malaria vaccine components can be readily used in humans

CF Suárez, L Pabón, A Barrera, J Aza-Conde… - Biochemical and …, 2017 - Elsevier
More than 50 years ago the owl monkey (genus Aotus) was found to be highly susceptible to
developing human malaria, making it an excellent experimental model for this disease …

Characterising a Microsatellite for DRB Typing in Aotus vociferans and Aotus nancymaae (Platyrrhini)

C López, CF Suárez, LF Cadavid, ME Patarroyo… - PLoS …, 2014 - journals.plos.org
Non-human primates belonging to the Aotus genus have been shown to be excellent
experimental models for evaluating drugs and vaccine candidates against malaria and other …

The Aotus nancymaae erythrocyte proteome and its importance for biomedical research

DA Moreno-Perez, R Garcia-Valiente, N Ibarrola… - Journal of …, 2017 - Elsevier
The Aotus nancymaae species has been of great importance in researching the biology and
pathogenesis of malaria, particularly for studying Plasmodium molecules for including them …

Reference strand conformational analysis (RSCA) is a valuable tool in identifying MHC-DRB sequences in three species of Aotus monkeys

JE Baquero, S Miranda, O Murillo, H Mateus, E Trujillo… - Immunogenetics, 2006 - Springer
The Aotus monkey has been of great value in the pre-clinical study of malaria vaccine
candidates. Several components of this primate's immune system have been studied and …

Gamma interferon levels and antibody production induced by two PvMSP-1 recombinant polypeptides are associated with protective immunity against P. vivax in …

CA Barrero, G Delgado, AY Sierra, Y Silva… - Vaccine, 2005 - Elsevier
Effector mechanisms responsible for providing protective immunity against Plasmodium
vivax (Pv) infection were examined in Aotus monkeys vaccinated with two Pv Merozoite …

The T-cell receptor in primates: identifying and sequencing new owl monkey TRBV gene sub-groups

CA Moncada, E Guerrero, P Cardenas, CF Suarez… - Immunogenetics, 2005 - Springer
Abstract The New World primate Aotus nancymaae (owl monkey) has been shown to be an
excellent experimental model when studying malarial parasites. Characterising the T-cell …