Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

Cell death is an essential biological process for physiological growth and development.
Three classical forms of cell death—apoptosis, autophagy, and necrosis—display distinct …

Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon,
inevitable in kidney transplantation and one of the most important mechanisms for non-or …

BECLIN1 is a well-established regulator of autophagy, a process essential for mammalian
survival. It functions in conjunction with other proteins to form Class III Phosphoinositide 3 …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Probiotic lactic acid bacteria (LAB) are a particular group of gram-positive bacteria that are
usually involved in natural ferments and widely used in food manufacture industry. Most of …

Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …

Abstract MCL1 (myeloid cell leukemia-1) is a widely recognized pro-survival member of the
Bcl-2 (B-cell lymphoma protein 2) family and a promising target for cancer therapy. While the …

Autophagy refers to a lysosomal degradative pathway or a process of self-cannibalization.
This pathway maintains nutrients levels for vital cellular functions during periods of …

BCL-2 family proteins are the regulators of apoptosis, but also have other functions. This
family of interacting partners includes inhibitors and inducers of cell death. Together they …