Impact of obesity on influenza A virus pathogenesis, immune response, and evolution

R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …

[HTML][HTML] The evolution of seasonal influenza viruses

VN Petrova, CA Russell - Nature Reviews Microbiology, 2018 - nature.com
Despite decades of surveillance and pharmaceutical and non-pharmaceutical interventions,
seasonal influenza viruses continue to cause epidemics around the world each year. The …

Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape

KR McCarthy, LJ Rennick, S Nambulli… - Science, 2021 - science.org
Zoonotic pandemics, such as that caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), can follow the spillover of animal viruses into highly susceptible human …

Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination

V Dhanasekaran, S Sullivan, KM Edwards… - Nature …, 2022 - nature.com
Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels
of morbidity, and substantial economic loss. Yet, global influenza circulation has been …

Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic

L Luzi, MG Radaelli - Acta diabetologica, 2020 - Springer
Aims Analyze the relationship between obesity and influenza. Methods Basal hormone
milieu, defective response of both innate and adaptive immune system and sedentariness …

Prolonged severe acute respiratory syndrome coronavirus 2 replication in an immunocompromised patient

JH Baang, C Smith, C Mirabelli… - The Journal of …, 2021 - academic.oup.com
We describe a case of chronic coronavirus disease 2019 (COVID-19) in a patient with
lymphoma and associated B-cell immunodeficiency. Viral cultures and sequence analysis …

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

TN Starr, AJ Greaney, A Addetia, WW Hannon… - Science, 2021 - science.org
Antibodies are a potential therapy for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), but the risk of the virus evolving to escape them remains unclear. Here we …

Co-evolution of immunity and seasonal influenza viruses

AX Han, SPJ de Jong, CA Russell - Nature Reviews Microbiology, 2023 - nature.com
Seasonal influenza viruses cause recurring global epidemics by continually evolving to
escape host immunity. The viral constraints and host immune responses that limit and drive …

Urbanization and humidity shape the intensity of influenza epidemics in US cities

BD Dalziel, S Kissler, JR Gog, C Viboud, ON Bjørnstad… - Science, 2018 - science.org
Influenza epidemics vary in intensity from year to year, driven by climatic conditions and by
viral antigenic evolution. However, important spatial variation remains unexplained. Here we …

[HTML][HTML] Functional evaluation of the P681H mutation on the proteolytic activation of the SARS-CoV-2 variant B. 1.1. 7 (Alpha) spike

B Lubinski, MHV Fernandes, L Frazier, T Tang… - Iscience, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent causing the
COVID-19 pandemic. SARS-CoV-2 B. 1.1. 7 (Alpha), a WHO variant of concern first …