The impact of systemic inflammation on Alzheimer's disease pathology
J Xie, L Van Hoecke, RE Vandenbroucke - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
Lipopolysaccharide-induced neuroinflammation as a bridge to understand neurodegeneration
CRA Batista, GF Gomes, E Candelario-Jalil… - International journal of …, 2019 - mdpi.com
A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …
pathological event triggering and perpetuating the neurodegenerative process associated …
Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential
X Ding, L Gao, Z Han, S Eleuteri, W Shi, Y Shen… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
Alzheimer's disease: etiology, neuropathology and pathogenesis
O Sheppard, M Coleman - Exon Publications, 2020 - exonpublications.com
Alzheimer's disease is the most common form of dementia and the most common
neurodegenerative disease. It manifests as a decline in short-term memory and cognition …
neurodegenerative disease. It manifests as a decline in short-term memory and cognition …
Gram-negative bacteria and their lipopolysaccharides in Alzheimer's disease: pathologic roles and therapeutic implications
H Kim, S Kim, SJ Shin, YH Park, Y Nam, C Kim… - Translational …, 2021 - Springer
Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and
causes destructive and irreversible cognitive decline. Failures in the development of …
causes destructive and irreversible cognitive decline. Failures in the development of …
A peripheral signature of Alzheimer's disease featuring microbiota-gut-brain axis markers
M Marizzoni, P Mirabelli, E Mombelli, L Coppola… - Alzheimer's Research & …, 2023 - Springer
Background Increasing evidence links the gut microbiota (GM) to Alzheimer's disease (AD)
but the mechanisms through which gut bacteria influence the brain are still unclear. This …
but the mechanisms through which gut bacteria influence the brain are still unclear. This …
The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer's disease
Alzheimer's Disease (AD) is the most common form of dementia, affecting almost 50 million
of people around the world, characterized by a complex and age-related progressive …
of people around the world, characterized by a complex and age-related progressive …
Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions
A Dovonou, C Bolduc, V Soto Linan, C Gora… - Translational …, 2023 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …
Inflammation in neurological disorders: the thin boundary between brain and periphery
C Cervellati, A Trentini, A Pecorelli… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Accumulating evidence suggests that inflammation is a major contributor in the
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …
Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer's disease
We studied the effects of systemic infection on brain cytokine level and cerebral vascular
function in Alzheimer's disease and vascular dementia, in superior temporal cortex …
function in Alzheimer's disease and vascular dementia, in superior temporal cortex …