Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain
tumors. The synuclein family consists of three members: α-, β-, and γ-synucleins present …

Synucleins are small, soluble proteins expressed primarily in neural tissues and certain
tumors. The family includes three known proteins: α‐synuclein, β‐synuclein, and γ …

Although α-synuclein is the main structural component of the insoluble filaments that form
Lewy bodies in Parkinson disease (PD), its physiological function and exact role in neuronal …

Transfection is a process by which oligonucleotides (DNA or RNA) are delivered into living
cells. This allows the synthesis of target proteins as well as their inhibition (gene silencing) …

Purpose Previous studies have described γ-synuclein as a protein highly expressed in
retinal ganglion cells (RGCs), and a loss of RGCs correlates with a downregulation of γ …

The synucleins are a small, soluble, highly conserved group of neuronal proteins that have
been implicated in both neurodegenerative diseases and cancer. The synuclein family …

Synuclein family consists of three members, α, β, and γ-synuclein. Due to their involvement
in human diseases, they have been thoroughly investigated for the last 30 years. Since the …

Background: Emerging evidence supports a role for glutamate in the biology of cancer. We
studied the impact of glutamate receptor subunit silencing on cancer phenotype. Materials …

Background Phosphatase of regenerating liver-3 (PRL-3) plays a causative role in tumor
metastasis, but the underlying mechanisms are not well understood. In our previous study …

Purpose: Perineural invasion is associated with the high incidence of local recurrence and a
dismal prognosis in pancreatic cancer. We previously reported a novel perineural invasion …