[HTML][HTML] Images as drivers of progress in cardiac computational modelling

P Lamata, R Casero, V Carapella, SA Niederer… - Progress in biophysics …, 2014 - Elsevier
Computational models have become a fundamental tool in cardiac research. Models are
evolving to cover multiple scales and physical mechanisms. They are moving towards …

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop

B Rodriguez, A Carusi, N Abi-Gerges, R Ariga… - Ep …, 2015 - academic.oup.com
Both biomedical research and clinical practice rely on complex datasets for the physiological
and genetic characterization of human hearts in health and disease. Given the complexity …

[HTML][HTML] Chaste: cancer, heart and soft tissue environment

FR Cooper, RE Baker, MO Bernabeu… - Journal of Open …, 2020 - ncbi.nlm.nih.gov
Chaste: Cancer, Heart and Soft Tissue Environment - PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

Biomechanical properties and microstructure of neonatal porcine ventricles

F Ahmad, J Liao, S Soe, MD Jones, J Miller… - Journal of the …, 2018 - Elsevier
Neonatal heart disorders represent a major clinical challenge, with congenital heart disease
alone affecting 36,000 new-borns annually within the European Union. Surgical intervention …

Bioelectrical effects of mechanical feedbacks in a strongly coupled cardiac electro-mechanical model

P Colli Franzone, LF Pavarino… - Mathematical Models and …, 2016 - World Scientific
The aim of this work is to investigate by means of numerical simulations the effects of
myocardial deformation due to muscle contraction on the bioelectrical activity of the cardiac …

Transmural gradients of myocardial structure and mechanics: implications for fiber stress and strain in pressure overload

ED Carruth, AD McCulloch, JH Omens - Progress in biophysics and …, 2016 - Elsevier
Although a truly complete understanding of whole heart activation, contraction, and
deformation is well beyond our current reach, a significant amount of effort has been …

[HTML][HTML] Determinants of biventricular cardiac function: a mathematical model study on geometry and myofiber orientation

M Pluijmert, T Delhaas, AF de la Parra, W Kroon… - … and modeling in …, 2017 - Springer
In patient-specific mathematical models of cardiac electromechanics, usually a patient-
specific geometry and a generic myofiber orientation field are used as input, upon which …

Influence of fiber connectivity in simulations of cardiac biomechanics

D Gil, R Aris, A Borras, E Ramírez, R Sebastian… - International journal of …, 2019 - Springer
Purpose Personalized computational simulations of the heart could open up new improved
approaches to diagnosis and surgery assistance systems. While it is fully recognized that …

Active contraction of the cardiac ventricle and distortion of the microstructural architecture

S Pezzuto, D Ambrosi - International journal for numerical …, 2014 - Wiley Online Library
The shortening of the myocardial fibers is the microstructural engine that produces the
contraction of the cardiac muscle. The complex interplay between fibers shortening and …

Transmural fibre orientations based on Laplace–Dirichlet-Rule-Based-Methods and their influence on human heart simulations

D Holz, D Martonová, E Schaller, MT Duong… - Journal of …, 2023 - Elsevier
It is well known that the orthotropic tissue structure decisively influences the mechanical and
electrical properties of the heart. Numerous approaches to compute the orthotropic tissue …