Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

LC Morley, T Tang, E Yasmin… - Cochrane Database …, 2017 - cochranelibrary.com
Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …

Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review

S Palomba, A Falbo, F Zullo, F Orio Jr - Endocrine reviews, 2009 - academic.oup.com
Metformin is an insulin sensitizer widely used for the treatment of patients affected by type 2
diabetes mellitus. Because many women with polycystic ovary syndrome (PCOS) are insulin …

Identifying children at risk for polycystic ovary syndrome

RL Rosenfield - The Journal of Clinical Endocrinology & …, 2007 - academic.oup.com
Context: Polycystic ovary syndrome (PCOS) appears to arise as a complex trait with
contributions from both heritable and nonheritable factors. Polygenic influences appear to …

Amenorrhea: an approach to diagnosis and management

DA Klein, MA Poth - American family physician, 2013 - aafp.org
Although amenorrhea may result from a number of different conditions, a systematic
evaluation including a detailed history, physical examination, and laboratory assessment of …

A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome

W Wei, H Zhao, A Wang, M Sui, K Liang… - European journal of …, 2012 - academic.oup.com
Objective Polycystic ovary syndrome (PCOS) is a frequent reproductive and metabolic
disorder associated with insulin resistance (IR). Berberine (BBR) is an isoquinoline …

[HTML][HTML] The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study

JG Wang, RA Anderson, GM Graham III, MC Chu… - Fertility and sterility, 2007 - Elsevier
Cinnamon extract has been shown to reduce insulin resistance in in vitro and in vivo studies
by increasing phosphatidylinositol 3-kinase activity in the insulin signaling pathway and thus …

Experts' opinion on inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: A further help for human reproduction and beyond

F Facchinetti, M Appetecchia, C Aragona… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: This Experts' opinion provides an updated scientific support to
gynecologists, obstetricians, endocrinologists, nutritionists, neurologists and general …

The role of metformin in polycystic ovary syndrome: a systematic review

E Moll, F van der Veen… - Human reproduction …, 2007 - academic.oup.com
This meta-analysis evaluated the effectiveness of metformin in subfertile women with
polycystic ovary syndrome (PCOS). Only randomized trials investigating the effectiveness of …

Advanced glycation end products and their relevance in female reproduction

Z Merhi - Human Reproduction, 2014 - academic.oup.com
STUDY QUESTION Do advanced glycation end products (AGEs) and their receptors play a
role in female reproduction? SUMMARY ANSWER AGEs might contribute to the etiology of …

Metabonomics reveals plasma metabolic changes and inflammatory marker in polycystic ovary syndrome patients

L Sun, W Hu, Q Liu, Q Hao, B Sun… - Journal of proteome …, 2012 - ACS Publications
Polycystic ovary syndrome (PCOS) is a common, clinically heterogeneous endocrine
disorder affecting women of reproductive age, associated with endocrinopathy and …