Challenges and advances in clinical applications of mesenchymal stromal cells
T Zhou, Z Yuan, J Weng, D Pei, X Du, C He… - Journal of hematology & …, 2021 - Springer
Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority …
intensely investigated for clinical applications within the last decades. However, the majority …
A decade of progress in tissue engineering
A Khademhosseini, R Langer - Nature protocols, 2016 - nature.com
Tremendous progress has been achieved in the field of tissue engineering in the past
decade. Several major challenges laid down 10 years ago, have been studied, including …
decade. Several major challenges laid down 10 years ago, have been studied, including …
Manufacturing of primed mesenchymal stromal cells for therapy
JQ Yin, J Zhu, JA Ankrum - Nature biomedical engineering, 2019 - nature.com
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …
manufactured and developed as unique cell products by many different manufacturers and …
Peptides as multifunctional players in cancer therapy
SMP Vadevoo, S Gurung, HS Lee… - … & Molecular Medicine, 2023 - nature.com
Peptides exhibit lower affinity and a shorter half-life in the body than antibodies. Conversely,
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …
[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?
A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …
of clinical applications. For most of these applications, systemic delivery of the cells is …
Concise review: MSC adhesion cascade—insights into homing and transendothelial migration
F Nitzsche, C Müller, B Lukomska, J Jolkkonen… - Stem …, 2017 - academic.oup.com
Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in
regenerative medicine. To fully exert their potential, efficient homing and migration toward …
regenerative medicine. To fully exert their potential, efficient homing and migration toward …
Bone tissue engineering: recent advances and challenges
AR Amini, CT Laurencin… - Critical Reviews™ in …, 2012 - dl.begellhouse.com
The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …
is expected to double by 2020, especially in populations where aging is coupled with …
Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise
TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …
numerous clinical indications, including cancer, has significant promise. However, a …
Advances in porous scaffold design for bone and cartilage tissue engineering and regeneration
A Cheng, Z Schwartz, A Kahn, X Li, Z Shao… - … Engineering Part B …, 2019 - liebertpub.com
Tissue engineering of bone and cartilage has progressed from simple to sophisticated
materials with defined porosity, surface features, and the ability to deliver biological factors …
materials with defined porosity, surface features, and the ability to deliver biological factors …
[PDF][PDF] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …