[HTML][HTML] Inclisiran: a new generation of lipid-lowering siRNA therapeutic

Y Zhang, H Chen, L Hong, H Wang, B Li… - Frontiers in …, 2023 - frontiersin.org
Atherosclerotic heart disease (AHD) is a major cause of morbidity and mortality worldwide.
Lowering low-density lipoprotein cholesterol (LDL-C) levels is a key strategy to prevent and …

Effectiveness and safety of injectable PCSK9 inhibitors in dyslipidaemias' treatment and cardiovascular disease prevention: An overview of 86 systematic reviews and …

K Pamporis, P Karakasis, S Simantiris, M Sagris… - Clínica e Investigación …, 2023 - Elsevier
Objective Multiple systematic reviews (SR) have been performed on the effects of proprotein
convertase subtilisin/kexin type 9 inhibitors (PCSK9i), often providing conflicting findings …

Inclisiran: A Novel Small Interfering RNA Drug for Low‐Density Lipoprotein Reduction

KW Smith, CM White - The Journal of Clinical Pharmacology, 2022 - Wiley Online Library
Inclisiran increases the number of low‐density lipoprotein surface receptors expressed on
hepatocytes using small interfering RNA directed against proprotein convertase …

[PDF][PDF] PCSK9 siRNA INHIBITOR INCLISIRAN AS A TREATMENT OPTION IN HYPERCHOLESTEROLEMIA: A BRIEF REVIEW.

ME Kılıç - Turkish Medical Student Journal, 2023 - researchgate.net
Dyslipidemia and hypercholesterolemia are global health issues that require urgent and
efficient treatments due to their major impact on cardiovascular disease. The incidence of …

[HTML][HTML] New and Emerging Options For Hypercholesterolemia

CM White - Meta, 2024 - pharmacypracticenews.com
This is a 2-part series designed to provide front-line pharmacists with knowledge of how to
use antihyperlipidemic drugs to reduce low-density lipoprotein (LDL) Read part 1 here.The …