RNA sequencing: the teenage years

R Stark, M Grzelak, J Hadfield - Nature Reviews Genetics, 2019 - nature.com
Over the past decade, RNA sequencing (RNA-seq) has become an indispensable tool for
transcriptome-wide analysis of differential gene expression and differential splicing of …

Mammary gland development: cell fate specification, stem cells and the microenvironment

JL Inman, C Robertson, JD Mott, MJ Bissell - Development, 2015 - journals.biologists.com
The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

[HTML][HTML] A human breast atlas integrating single-cell proteomics and transcriptomics

GK Gray, CMC Li, JM Rosenbluth, LM Selfors… - Developmental cell, 2022 - cell.com
The breast is a dynamic organ whose response to physiological and pathophysiological
conditions alters its disease susceptibility, yet the specific effects of these clinical variables …

[图书][B] Reproducibility and replicability in science

National Academies of Sciences, Policy, Global Affairs… - 2019 - books.google.com
One of the pathways by which the scientific community confirms the validity of a new
scientific discovery is by repeating the research that produced it. When a scientific effort fails …

[HTML][HTML] Technology meets TILs: Deciphering T cell function in the-omics era

WH Hudson, A Wieland - Cancer cell, 2023 - cell.com
T cells are at the center of cancer immunology because of their ability to recognize mutations
in tumor cells and directly mediate cancer cell killing. Immunotherapies to rejuvenate …

Making sense of replications

BA Nosek, TM Errington - Elife, 2017 - elifesciences.org
Reproducibility in Cancer Biology: Making sense of replications | eLife Skip to Content eLife logo
eLife home page Menu Home Magazine Community About Search Alerts Submit your research …

An open investigation of the reproducibility of cancer biology research

TM Errington, E Iorns, W Gunn, FE Tan, J Lomax… - Elife, 2014 - elifesciences.org
It is widely believed that research that builds upon previously published findings has
reproduced the original work. However, it is rare for researchers to perform or publish direct …

Human mesenchymal stromal cells from different sources diverge in their expression of cell surface proteins and display distinct differentiation patterns

KC Elahi, G Klein, M Avci-Adali, KD Sievert… - Stem cells …, 2016 - Wiley Online Library
When germ‐free cell cultures became a laboratory routine, hopes were high for using this
novel technology for treatment of diseases or replacement of cells in patients suffering from …

Clinical applications of infrared and Raman spectroscopy: state of play and future challenges

MJ Baker, HJ Byrne, J Chalmers, P Gardner… - Analyst, 2018 - pubs.rsc.org
Vibrational spectroscopies, based on infrared absorption and/or Raman scattering provide a
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …

[HTML][HTML] CD271 as a marker to identify mesenchymal stem cells from diverse sources before culture

M Álvarez-Viejo, Y Menéndez-Menéndez… - World journal of stem …, 2015 - ncbi.nlm.nih.gov
Mesenchymal stem cells, due to their characteristics are ideal candidates for cellular
therapy. Currently, in culture these cells are defined by their adherence to plastic, specific …