Nowadays, orthodontic treatment has become increasingly popular. However, the biological
mechanisms of orthodontic tooth movement (OTM) have not been fully elucidated. We were …

Orthodontic tooth movement (OTM) is biologically based on the spatiotemporal remodeling
process in periodontium, the mechanisms of which remain obscure. Noncoding RNAs …

MicroRNAs (miRs) play an important role in the development and remodeling of tissues
through the regulation of large cohorts of extracellular matrix (ECM) genes. The purpose of …

Human periodontal ligament-derived cells are important seed cells for periodontal
regeneration, and their osteogenic potential closely affects alveolar bone repair and …

Periodontal ligament (PDL), as a mechanical connection between the alveolar bone and
tooth, plays a pivotal role in force-induced orthodontic tooth movement (OTM). However …

During orthodontic tooth movement (OTM), periodontal ligament cells (PDLCs) receive the
mechanical stimuli and transform it into myofibroblasts (Mfbs). Indeed, previous studies have …

Anterior cruciate ligament (ACL) ruptures are usually treated with autograft implantation to
prevent knee instability. Tissue engineered ACL reconstruction is becoming promising to …

Myofibroblasts are specialized cells that play a key role in connective tissue remodeling and
reconstruction. Alpha-smooth muscle actin (α-SMA), vimentin and tenascin-C are …

Yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ)
are transcriptional coactivators encoded by paratactic homologous genes, shuttle‐crossing …

Objectives Periodontal ligament distraction (PDLD) can accelerate orthodontic tooth
movement (OTM). However, the effect of stretch frequency on osseous formation during …