In the past decade, RNA therapeutics have gone from being a promising concept to one of
the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what …

The introduction of more effective and selective mRNA delivery systems is required for the
advancement of many emerging biomedical technologies including the development of …

Due to the ease of use and excellent safety profile, ultrasound is a promising technique for
both diagnosis and site-specific therapy. Ultrasound-based techniques have been …

Engineered T cells expressing chimeric antigen receptors (CARs) have been proven as
efficacious therapies against selected hematological malignancies. However, the approved …

Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor
outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising …

Gastrointestinal tumors remain a significant healthcare burden worldwide, necessitating the
development of innovative therapeutic strategies. mRNA vaccines have emerged as a …

Small molecule drugs are increasingly emerging as innovative and effective treatments for
various diseases, with mRNA therapeutics being a notable representative. The success of …

Drug delivery systems aim at improving drug transport efficiency and therapeutic efficacy by
rational design, and current research on conventional delivery systems brings new …

As a promising strategy, gene delivery for cancer treatment accepts encouraging progress
due to its high efficacy, low toxicity, and exclusive selectivity. However, the delivery …

Messenger RNA (mRNA)-therapies have recently taken a huge step toward clinic thanks to
the first mRNA-based medicinal products marketed. mRNA features for clinical purposes are …