The buzz about hyaluronan (HA) is real. Whether found in face cream to increase water
volume loss and viscoelasticity or injected into the knee to restore the properties of synovial …

This review summarizes the atomic-resolution structural biology of hyaluronan and its
complexes available in the Protein Data Bank, as well as published studies of atomic …

Background Intervertebral disc (IVD) shows aging and degenerative changes earlier than
any other body connective tissue. Its repair and regeneration provide a considerable …

Multi-directional deformation exhibited by annulus fibrosus (AF) is contributed by chemo-
mechanical interactions among its biomolecular constituents' collagen type I (COL-I) …

Background Through bioinformatics analysis to identify the hub genes of Intervertebral disc
degeneration (IVDD) associated with basement membranes (BMs) and find out the potential …

Radial variation in water concentration from outer to inner lamellae is one of the
characteristic features of annulus fibrosus (AF). In addition, water concentration changes are …

In annulus fibrosus (AF), type I collagen (Col-I) dominates outer AF (OAF) while type II
collagen (Col-II) dominates inner AF (IAF). Using molecular dynamics simulations, this work …

Multi‐faceted deformation capabilities of Annulus Fibrosus (AF) results from an intricate
mechanical design by nature. Wherein, organization and interactions between the …

Background Previous studies observed that the intervertebral disc experiences the greatest
forces during spinal manipulative therapy (SMT) and that the distribution of forces among …

Diplomová práce se zabývá simulací dvou řetězců hyaluronanu sodného ve směsných
rozpouštědlech voda/1, 4-dioxan a voda/terc-butanol za dvou různých koncentrací NaCl …