Neurovascular coupling: motive unknown
PJ Drew - Trends in neurosciences, 2022 - cell.com
In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …
coupling. The common explanation for increased blood flow (known as functional …
Integrative regulation of human brain blood flow
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …
humans. We revisit important concepts from the older literature and describe the interaction …
False positives and false negatives in functional near-infrared spectroscopy: issues, challenges, and the way forward
I Tachtsidis, F Scholkmann - Neurophotonics, 2016 - spiedigitallibrary.org
We highlight a significant problem that needs to be considered and addressed when
performing functional near-infrared spectroscopy (fNIRS) studies, namely the possibility of …
performing functional near-infrared spectroscopy (fNIRS) studies, namely the possibility of …
[HTML][HTML] Insights into the pathogenesis of neurodegenerative diseases: Focus on mitochondrial dysfunction and oxidative stress
A Jurcau - International journal of molecular sciences, 2021 - mdpi.com
As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …
intensive research, important steps in the elucidation of pathogenetic cascades have been …
[HTML][HTML] What is the key mediator of the neurovascular coupling response?
PS Hosford, AV Gourine - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
The mechanisms of neurovascular coupling contribute to ensuring brain energy supply is
sufficient to meet demand. Despite significant research interest, the mechanisms underlying …
sufficient to meet demand. Despite significant research interest, the mechanisms underlying …
Relationship between simultaneously acquired resting-state regional cerebral glucose metabolism and functional MRI: a PET/MR hybrid scanner study
Recently introduced hybrid PET/MR scanners provide the opportunity to measure
simultaneously, and in direct spatial correspondence, both metabolic demand and functional …
simultaneously, and in direct spatial correspondence, both metabolic demand and functional …
[HTML][HTML] Energy metabolism decline in the aging brain—pathogenesis of neurodegenerative disorders
JW Błaszczyk - Metabolites, 2020 - mdpi.com
There is a growing body of evidencethat indicates that the aging of the brain results from the
decline of energy metabolism. In particular, the neuronal metabolism of glucose declines …
decline of energy metabolism. In particular, the neuronal metabolism of glucose declines …
Mechanisms mediating functional hyperemia in the brain
AR Nippert, KR Biesecker, EA Newman - The Neuroscientist, 2018 - journals.sagepub.com
Neuronal activity within the brain evokes local increases in blood flow, a response termed
functional hyperemia. This response ensures that active neurons receive sufficient oxygen …
functional hyperemia. This response ensures that active neurons receive sufficient oxygen …
[HTML][HTML] Erythrocytes are oxygen-sensing regulators of the cerebral microcirculation
HS Wei, H Kang, IYD Rasheed, S Zhou, N Lou… - Neuron, 2016 - cell.com
Energy production in the brain depends almost exclusively on oxidative metabolism.
Neurons have small energy reserves and require a continuous supply of oxygen (O 2). It is …
Neurons have small energy reserves and require a continuous supply of oxygen (O 2). It is …
[HTML][HTML] Mechanical and biological interactions of implants with the brain and their impact on implant design
D Prodanov, J Delbeke - Frontiers in neuroscience, 2016 - frontiersin.org
Neural prostheses have already a long history and yet the cochlear implant remains the only
success story about a longterm sensory function restoration. On the other hand, neural …
success story about a longterm sensory function restoration. On the other hand, neural …