By combining the enormous molecular diversity of the immune system with basic
mechanistic principles of chemistry, one can produce catalytic antibodies that allow control …

The first catalytic antibodies (abzymes) were reported in 1986. Since then abzymes
catalyzing various types of reactions have been reported. There have been a number of …

This article brings together all of the kinetic data on catalytic antibodies available in the
published literature at the time of writing (September, 1993). The data have been presented …

Antigen mimicry by anti‐idiotypic antibodies is investigated as a reliable strategy to achieve
molecular imprinting of an enzymatic activity. A monoclonal anti‐idiotypic antibody (Ab2 …

抄録 Six novel transition state analogs (TSAs) of cocaine (10-14 and 17) and one non-
cocaine, p-aminophenyl-phosphonyl ester of cyclohexanol (19), were synthesized and …

Kinetic characterization of enzymes and analogous catalysts such as catalytic antibodies
requires knowledge of the molarity of functional sites. Various stoichiometric titration …

The production and characterization of rabbit polyclonal antibodies that catalyze the
hydrolysis of trityl protecting groups is described. The catalytic activity increased throughout …

According to the classic approach, catalytic antibodies are elicited with haptens designed to
mimic presumed transition states of desired reactions. 1-5 Attention is usually focused on …

1 The hydrolytic activity of IgG purified from (a) 13 samples of ovine antiserum collected from
three animals during a two‐year immunisation programme using a phosphate immunogen …

Described herein is the synthesis of a hapten of biocyclo [2, 2, 2] octene 5 designed to mimic
the exo transition-state of an aza Diels–Alder reaction. Immunization of rabbits with this …