Pharmacotherapy for female sexual dysfunctions (FSDs): what is on the market and where is this field heading?

RE Nappi, L Tiranini, L Cucinella, E Martini… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Female sexual dysfunctions (FSDs) are common in women of any
age and have a huge impact on quality of life and relationships. They have a multifaceted …

Hair regrowth boosting via minoxidil cubosomes: formulation development, in vivo hair regrowth evaluation, histopathological examination and confocal laser …

A Makhlouf, T Elnawawy - International Journal of Pharmaceutics, 2023 - Elsevier
Minoxidil has been used as an effective and cost-efficient topical treatment for androgenic
alopecia. However, due to its poor water solubility, commercially available formulations …

[HTML][HTML] Compritol-based nanostrucutured lipid carriers (NLCs) for augmentation of zolmitriptan bioavailability via the transdermal route: in vitro optimization, ex vivo …

DH Hassan, JN Shohdy, DA El-Setouhy… - Pharmaceutics, 2022 - mdpi.com
Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing
headaches. Triptans are agonists for serotonin receptors. Zolmitriptan (ZMP) is a …

Development of canagliflozin nanocrystals sublingual tablets in the presence of sodium caprate permeability enhancer: formulation optimization, characterization, in …

S Fathy Elhabal, MA El-Nabarawi, N Abdelaal… - Drug Delivery, 2023 - Taylor & Francis
Canagliflozin (CFZ) is a sodium-glucose cotransporter-2 inhibitor (SGLT2) that lowers
albuminuria in type-2 diabetic patients, cardiovascular, kidney, and liver disease. CFZ is …

[HTML][HTML] Spanlastics as a potential platform for enhancing the brain delivery of flibanserin: in vitro response-surface optimization and in vivo pharmacokinetics …

WS Alharbi, RH Hareeri, M Bazuhair, MA Alfaleh… - Pharmaceutics, 2022 - mdpi.com
Flibanserin was licensed by the United States Food and Drug Administration (FDA) as an
oral non-hormonal therapy for pre-menopausal women with inhibited sexual desire disorder …

Enhanced bioavailability and pharmacokinetics parameters of Enalapril solid self nanoemulsifying oral dispersible tablet: Formulation, in vitro and in vivo evaluation

DH Hassan, AA Ammar, AA Ramadan… - Pharmaceutical …, 2023 - Taylor & Francis
Enalapril (EN) is an antihypertensive drug that is sparingly soluble in water with limited oral
bioavailability. Successfully prepared self-nanoemulsifying systems (SNES) loaded with EN …

Application of curcumin as a co-former and an efflux inhibitor in paclitaxel co-amorphous mixture

P Huang, H Yan, H Wu, L Liu, W Niu, B Zhai… - Journal of Drug Delivery …, 2023 - Elsevier
The co-amorphous (CAM) system has attracted widely attention for improving the solubility
of poor water solubility drug and provide a formulation strategy for combination …

Formulation and evaluation of baclofen-meloxicam orally disintegrating tablets (ODTs) using co-processed excipients and improvement of ODTs performance using …

R Abdelmonem, MM Abdellatif… - Drug Design …, 2021 - Taylor & Francis
Purpose This study aimed to formulate an orally disintegrating tablet (ODT) containing both
baclofen and meloxicam together for treating osteoarthritis. Methods Direct compression …

Flexosomes as a promising nanoplatform for enhancing tolnaftate ocular delivery: Formulation, in vitro characterization, statistical optimization, ex vivo and microbial in …

D Aziz, S Mohamed, S Tayel, A Makhlouf - International Journal of …, 2023 - Elsevier
The eye is a complex organ with a unique physiology and anatomy. Using novel
nanosystems is expected to enhance ocular drug permeation and retention. Hence, this …

[HTML][HTML] Nanocrystals and nanosuspensions: an exploration from classic formulations to advanced drug delivery systems

B Rossier, O Jordan, E Allémann… - Drug Delivery and …, 2024 - Springer
Nanocrystals and nanosuspensions have become realistic approaches to overcome the
formulation challenges of poorly water-soluble drugs. They also represent a less-known but …