Role of microbiota-gut-brain axis in regulating dopaminergic signaling
S Hamamah, A Aghazarian, A Nazaryan, A Hajnal… - Biomedicines, 2022 - mdpi.com
Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …
Digital addiction and sleep
B Dresp-Langley, A Hutt - … journal of environmental research and public …, 2022 - mdpi.com
In 2020, the World Health Organization formally recognized addiction to digital technology
(connected devices) as a worldwide problem, where excessive online activity and internet …
(connected devices) as a worldwide problem, where excessive online activity and internet …
Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer's Disease
E Spoleti, L La Barbera, E Cauzzi, ML De Paolis… - Molecular …, 2024 - nature.com
Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …
Tau-driven degeneration of sleep-and wake-regulating neurons in Alzheimer's disease
Disturbances of the sleep/wake cycle in Alzheimer's disease (AD) are common, frequently
precede cognitive decline, and tend to worsen with disease progression. Sleep is critical to …
precede cognitive decline, and tend to worsen with disease progression. Sleep is critical to …
The role of sonic hedgehog pathway in the development of the central nervous system and aging-related neurodegenerative diseases
C Yang, Y Qi, Z Sun - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The Sonic hedgehog (SHH) pathway affects neurogenesis and neural patterning during the
development of the central nervous system. Dysregulation of the SHH pathway in the brain …
development of the central nervous system. Dysregulation of the SHH pathway in the brain …
[HTML][HTML] Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease
We have developed an efficient approach to generate functional induced dopaminergic (DA)
neurons from adult human dermal fibroblasts. When performing DA neuronal conversion of …
neurons from adult human dermal fibroblasts. When performing DA neuronal conversion of …
Weight loss and malnutrition in patients with Parkinson's disease: current knowledge and future prospects
K Ma, N Xiong, Y Shen, C Han, L Liu… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's Disease (PD) is currently considered a systemic neurodegenerative disease
manifested with not only motor but also non-motor symptoms. In particular, weight loss and …
manifested with not only motor but also non-motor symptoms. In particular, weight loss and …
Viral involvement in Alzheimer's disease
Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …
Milk's role as an epigenetic regulator in health and disease
BC Melnik, G Schmitz - Diseases, 2017 - mdpi.com
It is the intention of this review to characterize milk's role as an epigenetic regulator in health
and disease. Based on translational research, we identify milk as a major epigenetic …
and disease. Based on translational research, we identify milk as a major epigenetic …
[HTML][HTML] Cholecystokinin (CCK): a neuromodulator with therapeutic potential in Alzheimer's and Parkinson's disease
N Reich, C Hölscher - Frontiers in Neuroendocrinology, 2024 - Elsevier
Cholecystokinin (CCK) is a neuropeptide modulating digestion, glucose levels,
neurotransmitters and memory. Recent studies suggest that CCK exhibits neuroprotective …
neurotransmitters and memory. Recent studies suggest that CCK exhibits neuroprotective …