Targeting and engineering long non-coding RNAs for cancer therapy

M Coan, S Haefliger, S Ounzain, R Johnson - Nature Reviews Genetics, 2024 - nature.com
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …

Recent applications of artificial intelligence in RNA-targeted small molecule drug discovery

EC Morishita, S Nakamura - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
ABSTRACT Introduction Targeting RNAs with small molecules offers an alternative to the
conventional protein-targeted drug discovery and can potentially address unmet and …

Targeting epigenetic deregulations for the management of esophageal carcinoma: recent advances and emerging approaches

P Ahuja, R Yadav, S Goyal, C Yadav, S Ranga… - Cell Biology and …, 2023 - Springer
Ranking from seventh in incidence to sixth in mortality, esophageal carcinoma is considered
a severe malignancy of food pipe. Later-stage diagnosis, drug resistance, and a high …