Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery
DNA variation analysis has become indispensable in many aspects of modern biomedicine,
most prominently in the comparison of normal and tumor samples. Thousands of samples …
most prominently in the comparison of normal and tumor samples. Thousands of samples …
[HTML][HTML] Targeting the limbic system: insights into its involvement in tinnitus
Tinnitus is originally derived from the Latin verb tinnire, which means “to ring”. Tinnitus, a
complex disorder, is a result of sentient cognizance of a sound in the absence of an external …
complex disorder, is a result of sentient cognizance of a sound in the absence of an external …
A Systematic Review on Heritability of Sudden Sensorineural Hearing Loss
MÁ Yélamos Lorente, P Perez‐Carpena… - The …, 2024 - Wiley Online Library
Objective To assess the evidence supporting the heritability and genetic basis of sudden
sensorineural hearing loss (SSNHL). Data Source Records were extracted from PubMed …
sensorineural hearing loss (SSNHL). Data Source Records were extracted from PubMed …
[HTML][HTML] A Systematic Review on the Genetic Contribution to Tinnitus
P Perez-Carpena, JA Lopez-Escamez… - Journal of the …, 2024 - Springer
Purpose To assess the available evidence to support a genetic contribution and define the
role of common and rare variants in tinnitus. Methods After a systematic search and quality …
role of common and rare variants in tinnitus. Methods After a systematic search and quality …
[HTML][HTML] The Relevance of Autophagy within Inner Ear in Baseline Conditions and Tinnitus-Related Syndromes
G Lazzeri, F Biagioni, M Ferrucci… - International Journal of …, 2023 - mdpi.com
Tinnitus is the perception of noise in the absence of acoustic stimulation (phantom noise). In
most patients suffering from chronic peripheral tinnitus, an alteration of outer hair cells …
most patients suffering from chronic peripheral tinnitus, an alteration of outer hair cells …
[HTML][HTML] Rare Deletions or Large Duplications Contribute to Genetic Variation in Patients with Severe Tinnitus and Meniere Disease
A Escalera-Balsera, AM Parra-Perez… - Genes, 2023 - mdpi.com
Meniere disease (MD) is a debilitating disorder of the inner ear defined by sensorineural
hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which …
hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which …
[HTML][HTML] Transcriptional-profile changes in the medial geniculate body after noise-induced tinnitus
P Liu, X Xue, C Zhang, H Zhou, Z Ding… - … Biology and Medicine, 2024 - ncbi.nlm.nih.gov
Tinnitus is a disturbing condition defined as the occurrence of acoustic hallucinations with
no actual sound. Although the mechanisms underlying tinnitus have been explored …
no actual sound. Although the mechanisms underlying tinnitus have been explored …
Neuron navigators: A novel frontier with physiological and pathological implications
Neuron navigators are microtubule plus-end tracking proteins containing basic and serine
rich regions which are encoded by neuron navigator genes (NAVs). Neuron navigator …
rich regions which are encoded by neuron navigator genes (NAVs). Neuron navigator …