[HTML][HTML] Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine
S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
[HTML][HTML] Recombinant viral vectors for therapeutic programming of tumour microenvironment: Advantages and limitations
K Spunde, K Korotkaja, A Zajakina - Biomedicines, 2022 - mdpi.com
Viral vectors have been widely investigated as tools for cancer immunotherapy. Although
many preclinical studies demonstrate significant virus-mediated tumour inhibition in synergy …
many preclinical studies demonstrate significant virus-mediated tumour inhibition in synergy …
Intratumoral delivery of immunotherapy to treat breast cancer: current development in clinical and preclinical studies
Breast cancer poses one of the largest threats to women's health. Treatment continues to
improve for all the subtypes of breast cancer, but some subtypes, such as triple negative …
improve for all the subtypes of breast cancer, but some subtypes, such as triple negative …
[HTML][HTML] Establishment and Characterization of Free-Floating 3D Macrophage Programming Model in the Presence of Cancer Cell Spheroids
Reprogramming of tumor-associated macrophages (TAMs) is a promising strategy for
cancer immunotherapy. Several studies have shown that cancer cells induce/support the …
cancer immunotherapy. Several studies have shown that cancer cells induce/support the …
3D Coculture between Cancer Cells and Macrophages: From Conception to Experimentation
R Quoniou, E Moreau, F Cachin… - ACS Biomaterials …, 2023 - ACS Publications
A tumor is a complex cluster with many types of cells in the microenvironment that help it
grow. Macrophages, immune cells whose main role is to maintain body homeostasis …
grow. Macrophages, immune cells whose main role is to maintain body homeostasis …
[HTML][HTML] Fibronectin functions as a selective agonist for distinct toll-like receptors in triple-negative breast Cancer
A Ambesi, P Maddali, PJ McKeown-Longo - Cells, 2022 - mdpi.com
The microenvironment of tumors is characterized by structural changes in the fibronectin
matrix, which include increased deposition of the EDA isoform of fibronectin and the …
matrix, which include increased deposition of the EDA isoform of fibronectin and the …
[HTML][HTML] Proceedings of the Online Conference “Vaccines and Vaccination during and Post COVID Pandemics”(7–9 December 2022)
L Sokolovska, M Isaguliants, FM Buonaguro - 2023 - mdpi.com
The COVID-19 pandemic put focus on various aspects of vaccine research and
development. These include mass vaccination strategies, vaccination compliance and …
development. These include mass vaccination strategies, vaccination compliance and …
[HTML][HTML] Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes
Q Li, H Liu, Y Jin, Y Yu, Y Wang, D Wu, Y Guo… - Computers in Biology …, 2023 - Elsevier
Breast cancer, which is the most common malignant tumor among women worldwide and an
important cause of death in women. The existing prognostic model for patients with breast …
important cause of death in women. The existing prognostic model for patients with breast …
[HTML][HTML] Styrylpyridinium Derivatives for Fluorescent Cell Imaging
R Putralis, K Korotkaja, M Kaukulis, Z Rudevica… - Pharmaceuticals, 2023 - mdpi.com
A set of styrylpyridinium (SP) compounds was synthesised in order to study their
spectroscopic and cell labelling properties. The compounds comprised different electron …
spectroscopic and cell labelling properties. The compounds comprised different electron …
[HTML][HTML] Perspective Technologies of Vaccination: Do We Still Need Old Vaccines?
M Isaguliants, FJ Burt - Vaccines, 2022 - mdpi.com
Until December 2019, we were living in the world of successfully functioning vaccines and
vaccination programs. Smallpox was eradicated, polio close to being eradicated, HBV …
vaccination programs. Smallpox was eradicated, polio close to being eradicated, HBV …