Host–microbiota interactions in inflammatory bowel disease
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
The human gut microbiome–a potential controller of wellness and disease
Interest toward the human microbiome, particularly gut microbiome has flourished in recent
decades owing to the rapidly advancing sequence-based screening and humanized …
decades owing to the rapidly advancing sequence-based screening and humanized …
Human memory T cells: generation, compartmentalization and homeostasis
Memory T cells constitute the most abundant lymphocyte population in the body for the
majority of a person's lifetime; however, our understanding of memory T cell generation …
majority of a person's lifetime; however, our understanding of memory T cell generation …
Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
C Burrello, F Garavaglia, FM Cribiù, G Ercoli… - Nature …, 2018 - nature.com
Alteration of the gut microbiota has been associated with different gastrointestinal disorders.
Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a …
Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a …
Circulating and tissue-resident CD4+ T cells with reactivity to intestinal microbiota are abundant in healthy individuals and function is altered during inflammation
Background & Aims Interactions between commensal microbes and the immune system are
tightly regulated and maintain intestinal homeostasis, but little is known about these …
tightly regulated and maintain intestinal homeostasis, but little is known about these …
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity
EM Eshleman, TY Shao, V Woo, T Rice… - The Journal of …, 2023 - Am Soc Clin Investig
Aberrant immune responses to resident microbes promote inflammatory bowel disease and
other chronic inflammatory conditions. However, how microbiota-specific immunity is …
other chronic inflammatory conditions. However, how microbiota-specific immunity is …
[HTML][HTML] Ecological and evolutionary forces shaping microbial diversity in the human intestine
RE Ley, DA Peterson, JI Gordon - Cell, 2006 - cell.com
The human gut is populated with as many as 100 trillion cells, whose collective genome, the
microbiome, is a reflection of evolutionary selection pressures acting at the level of the host …
microbiome, is a reflection of evolutionary selection pressures acting at the level of the host …
Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis
The microbiota of the mammalian intestine depend largely on dietary polysaccharides as
energy sources. Most of these polymers are not degradable by the host, but herbivores can …
energy sources. Most of these polymers are not degradable by the host, but herbivores can …
The immunology of mucosal models of inflammation
W Strober, IJ Fuss, RS Blumberg - Annual review of …, 2002 - annualreviews.org
In recent years the status of the inflammatory bowel diseases (IBDs) as canonical
autoimmune diseases has risen steadily with the recognition that these diseases are, at their …
autoimmune diseases has risen steadily with the recognition that these diseases are, at their …
Dysbiosis in inflammatory bowel disease
CP Tamboli, C Neut, P Desreumaux, JF Colombel - Gut, 2004 - gut.bmj.com
Abundant data have incriminated intestinal bacteria in the initiation and amplification stages
of inflammatory bowel diseases. However, the precise role of intestinal bacteria remains …
of inflammatory bowel diseases. However, the precise role of intestinal bacteria remains …