Gold nanoparticles and gold nanorods in the landscape of cancer therapy

P Kesharwani, R Ma, L Sang, M Fatima, A Sheikh… - Molecular cancer, 2023 - Springer
Cancer is a grievous disease whose treatment requires a more efficient, non-invasive
therapy, associated with minimal side effects. Gold nanoparticles possessing greatly …

Tumor microenvironment complexity and therapeutic implications at a glance

R Baghban, L Roshangar… - Cell Communication and …, 2020 - Springer
The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …

Hybrid nanosystems for biomedical applications

J Seaberg, H Montazerian, MN Hossen… - ACS …, 2021 - ACS Publications
Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …

Openwork@ dendritic mesoporous silica nanoparticles for lactate depletion and tumor microenvironment regulation

J Tang, AK Meka, S Theivendran, Y Wang… - Angewandte …, 2020 - Wiley Online Library
The direct depletion of lactate accumulated in the tumor microenvironment holds promise for
cancer therapy but remains challenging. Herein, we report a one‐pot synthesis of …

Fibroblasts in the tumor microenvironment

M Truffi, L Sorrentino, F Corsi - Tumor microenvironment: Non …, 2020 - Springer
The implications of a tumor microenvironment in cancer initiation and progression have
drawn interest in recent years. Within the tumor stroma, fibroblasts represent a predominant …

The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy

J He, S Liu, Y Zhang, X Chu, Z Lin, Z Zhao… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy of malignant tumor is a verified and crucial anti-tumor strategy to help
patients with cancer for prolonging prognostic survival. It is a novel anticancer tactics that …

Strategies for delivering nanoparticles across tumor blood vessels

V Sheth, L Wang, R Bhattacharya… - Advanced functional …, 2021 - Wiley Online Library
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …

Nano-targeting vascular remodeling in cancer: recent developments and future directions

R Giordo, Z Wehbe, P Paliogiannis, AH Eid… - Seminars in Cancer …, 2022 - Elsevier
Tumor growth and progression are strictly dependent on the adequate blood supply of
oxygen and nutrients. The formation of new blood vessels and vascular networks is …

Nanoparticle interactions with the tumor microenvironment

Y Huai, MN Hossen, S Wilhelm… - Bioconjugate …, 2019 - ACS Publications
Compared to normal tissues, the tumor microenvironment (TME) has a number of aberrant
characteristics including hypoxia, acidosis, and vascular abnormalities. Many researchers …

Self-therapeutic nanomaterials: Applications in biology and medicine

J Seaberg, JR Clegg, R Bhattacharya, P Mukherjee - Materials Today, 2023 - Elsevier
Over past decades, nanotechnology has contributed to the biomedical field in areas
including detection, diagnosis, and drug delivery via opto-electronic properties or …