Antibody-drug conjugates and ocular toxicity
M Jaffry, H Choudhry, OM Aftab… - Journal of Ocular …, 2023 - liebertpub.com
Antibody-drug conjugates (ADCs) are a growing class of chemotherapeutic agents for the
purpose of treating cancers that often have relapsed or failed first-and second-line …
purpose of treating cancers that often have relapsed or failed first-and second-line …
Ocular toxicities associated with antibody drug conjugates
RF Marshall, H Xu, M Berkenstock - Current Opinion in …, 2024 - journals.lww.com
Ocular toxicities associated with antibody drug conjugates Page 1 ICU 350601 CURRENT
OPINION Ocular toxicities associated with antibody drug conjugates Rayna F. Marshalla …
OPINION Ocular toxicities associated with antibody drug conjugates Rayna F. Marshalla …
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution
BS Vollmar, M Fei, WC Liang, DD Bravo… - Bioconjugate …, 2022 - ACS Publications
Here, we explore whether PEGylation of antibodies can modulate their biodistribution to the
eye, an organ once thought to be immune privileged but has recently been shown to be …
eye, an organ once thought to be immune privileged but has recently been shown to be …
Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in The Mouse Eye Following Intravitreal Administration
D Bussing, Y Li, L Guo, A Verma, JM Sullivan… - Journal of …, 2023 - Elsevier
Mice are rarely used in pharmacokinetic (PK) studies of ocular therapeutics due to the small
size of their eyes and challenges in drug administration, tissue collection, and analysis of …
size of their eyes and challenges in drug administration, tissue collection, and analysis of …