International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy
MP Abbracchio, G Burnstock, JM Boeynaems… - Pharmacological …, 2006 - ASPET
There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …
signaling since the last review published by our International Union of Pharmacology …
Cellular distribution and functions of P2 receptor subtypes in different systems
G Burnstock, GE Knight - Int Rev Cytol, 2004 - books.google.com
In 1929 Drury and Szent-Györgyi published a seminal paper describing the potent actions of
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …
Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future
G Burnstock - Bioessays, 2012 - Wiley Online Library
Abstract Adenosine 5′‐triphosphate (ATP) was identified in 1970 as the transmitter
responsible for non‐adrenergic, non‐cholinergic neurotransmission in the gut and bladder …
responsible for non‐adrenergic, non‐cholinergic neurotransmission in the gut and bladder …
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice
C Léon, B Hechler, M Freund, A Eckly… - The Journal of …, 1999 - Am Soc Clin Investig
ADP is a key agonist in hemostasis and thrombosis. ADP-induced platelet activation
involves the purinergic P2Y1 receptor, which is responsible for shape change through …
involves the purinergic P2Y1 receptor, which is responsible for shape change through …
Evolutionary origins of the purinergic signalling system
G Burnstock, A Verkhratsky - Acta physiologica, 2009 - Wiley Online Library
Purines appear to be the most primitive and widespread chemical messengers in the animal
and plant kingdoms. The evidence for purinergic signalling in plants, invertebrates and …
and plant kingdoms. The evidence for purinergic signalling in plants, invertebrates and …
Introduction: P2 receptors
G Burnstock - Current topics in medicinal chemistry, 2004 - ingentaconnect.com
The current status of ligand gated ion channel P2X and G protein-coupled P2Y receptor
subtypes is described. This is followed by a summary of what is known of the distribution and …
subtypes is described. This is followed by a summary of what is known of the distribution and …
Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death
G Burnstock, A Verkhratsky - Cell death & disease, 2010 - nature.com
The purinergic signalling system, which uses purines and pyrimidines as chemical
transmitters, and purinoceptors as effectors, is deeply rooted in evolution and development …
transmitters, and purinoceptors as effectors, is deeply rooted in evolution and development …
Involvement of P2 receptors in the growth and survival of neurons in the CNS
H Franke, P Illes - Pharmacology & therapeutics, 2006 - Elsevier
Extracellular adenosine 5′-triphosphate (ATP) has been recognized as a ubiquitous,
unstable signalling molecule, acting as a fast neurotransmitter and modulator of transmitter …
unstable signalling molecule, acting as a fast neurotransmitter and modulator of transmitter …
Nucleotide signaling in nervous system development
H Zimmermann - Pflügers Archiv, 2006 - Springer
The development of the nervous system requires complex series of cellular programming
and intercellular communication events that lead from the early neural induction to the …
and intercellular communication events that lead from the early neural induction to the …
Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells
PB Tran, D Ren, TJ Veldhouse… - Journal of neuroscience …, 2004 - Wiley Online Library
We investigated the expression and functions of chemokine receptors in neural progenitor
cells isolated from embryonic and adult mice. Reverse transcriptase‐polymerase chain …
cells isolated from embryonic and adult mice. Reverse transcriptase‐polymerase chain …