New insights into the development of the human cerebral cortex

Z Molnár, GJ Clowry, N Šestan, A Alzu'bi… - Journal of …, 2019 - Wiley Online Library
The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …

Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

A multimodal cell census and atlas of the mammalian primary motor cortex

Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

Multi-omic single-cell velocity models epigenome–transcriptome interactions and improves cell fate prediction

C Li, MC Virgilio, KL Collins, JD Welch - Nature biotechnology, 2023 - nature.com
Multi-omic single-cell datasets, in which multiple molecular modalities are profiled within the
same cell, offer an opportunity to understand the temporal relationship between epigenome …

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

S Zhong, S Zhang, X Fan, Q Wu, L Yan, J Dong… - Nature, 2018 - nature.com
The mammalian prefrontal cortex comprises a set of highly specialized brain areas
containing billions of cells and serves as the centre of the highest-order cognitive functions …

Genetic dissection of the glutamatergic neuron system in cerebral cortex

KS Matho, D Huilgol, W Galbavy, M He, G Kim, X An… - Nature, 2021 - nature.com
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …

[HTML][HTML] Molecular identity of human outer radial glia during cortical development

AA Pollen, TJ Nowakowski, J Chen, H Retallack… - Cell, 2015 - cell.com
Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular
zone and outer subventricular zone. Although outer subventricular zone radial glia may …

Generating neuronal diversity in the mammalian cerebral cortex

S Lodato, P Arlotta - Annual review of cell and developmental …, 2015 - annualreviews.org
The neocortex is the part of the brain responsible for execution of higher-order brain
functions, including cognition, sensory perception, and sophisticated motor control. During …

Development and evolution of thalamocortical connectivity

Z Molnár, KY Kwan - Cold Spring Harbor Perspectives in …, 2024 - cshperspectives.cshlp.org
Conscious perception in mammals depends on precise circuit connectivity between cerebral
cortex and thalamus; the evolution and development of these structures are closely linked …

Evolution of cortical neurogenesis in amniotes controlled by robo signaling levels

A Cárdenas, A Villalba, C de Juan Romero, E Picó… - Cell, 2018 - cell.com
Cerebral cortex size differs dramatically between reptiles, birds, and mammals, owing to
developmental differences in neuron production. In mammals, signaling pathways …