Function and evolution of vertebrate globins
T Burmester, T Hankeln - Acta Physiologica, 2014 - Wiley Online Library
Globins are haem‐proteins that bind O2 and thus play an important role in the animal's
respiration and oxidative energy production. However, globins may also have other …
respiration and oxidative energy production. However, globins may also have other …
No oxygen? No problem! Intrinsic brain tolerance to hypoxia in vertebrates
Many vertebrates are challenged by either chronic or acute episodes of low oxygen
availability in their natural environments. Brain function is especially vulnerable to the effects …
availability in their natural environments. Brain function is especially vulnerable to the effects …
Reactive glial cells: increased stiffness correlates with increased intermediate filament expression
YB Lu, I Iandiev, M Hollborn, N Körber… - The FASEB …, 2011 - Wiley Online Library
Increased stiffness of reactive glial cells may impede neurite growth and contribute to the
poor regenerative capabilities of the mammalian central nervous system. We induced …
poor regenerative capabilities of the mammalian central nervous system. We induced …
Neuroglobin: From structure to function in health and disease
P Ascenzi, A di Masi, L Leboffe, M Fiocchetti… - Molecular aspects of …, 2016 - Elsevier
In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax
A Avivi, F Gerlach, A Joel, S Reuss… - Proceedings of the …, 2010 - National Acad Sciences
The subterranean mole rat Spalax is an excellent model for studying adaptation of a
mammal toward chronic environmental hypoxia. Neuroglobin (Ngb) and cytoglobin (Cygb) …
mammal toward chronic environmental hypoxia. Neuroglobin (Ngb) and cytoglobin (Cygb) …
A review of the multi-level adaptations for maximizing aerobic dive duration in marine mammals: from biochemistry to behavior
RW Davis - Journal of Comparative Physiology B, 2014 - Springer
Marine mammals exhibit multi-level adaptations, from cellular biochemistry to behavior, that
maximize aerobic dive duration. A dive response during aerobic dives enables the efficient …
maximize aerobic dive duration. A dive response during aerobic dives enables the efficient …
Neuroglobin protects astroglial cells from hydrogen peroxide‐induced oxidative stress and apoptotic cell death
F Amri, I Ghouili, M Amri, A Carrier… - Journal of …, 2017 - Wiley Online Library
Oxidative stress, resulting from accumulation of reactive oxygen species, plays a critical role
in astroglial cell death occurring in diverse neuropathological conditions. Numerous studies …
in astroglial cell death occurring in diverse neuropathological conditions. Numerous studies …
17β‐Oestradiol anti‐inflammatory effects in primary astrocytes require oestrogen receptor β‐mediated neuroglobin up‐regulation
E De Marinis, E Acaz‐Fonseca… - Journal of …, 2013 - Wiley Online Library
Neuroglobin (Ngb), so named after its initial discovery in brain neurones, has received great
attention as a result of its neuroprotective effects both in vitro and in vivo. Recently, we …
attention as a result of its neuroprotective effects both in vitro and in vivo. Recently, we …
Breath-hold diving–the physiology of diving deep and returning
A Patrician, Ž Dujić, B Spajić, I Drviš… - Frontiers in …, 2021 - frontiersin.org
Breath-hold diving involves highly integrative physiology and extreme responses to both
exercise and asphyxia during progressive elevations in hydrostatic pressure. With …
exercise and asphyxia during progressive elevations in hydrostatic pressure. With …
Old proteins–new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells
TA Gorr, D Wichmann, C Pilarsky… - Acta …, 2011 - Wiley Online Library
Aim: The unexpected identification of myoglobin (MB) in breast cancer prompted us to
evaluate the clinico‐pathological value of MB, haemoglobin (HB) and cytoglobin (CYGB) in …
evaluate the clinico‐pathological value of MB, haemoglobin (HB) and cytoglobin (CYGB) in …