Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Association of Neurological Surgeons and Congress of Neurological Surgeons published
the first evidence-based guidelines for the management of patients with acute cervical spinal …

Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …

Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …

Spinal cord and brain injuries lead to complex cellular and molecular interactions within the
central nervous system in an attempt to repair the initial tissue damage. Many studies have …

Spinal cord injury (SCI) can cause permanent loss of sensory and motor function, and there
is no effective clinical treatment, to date. Due to the complex pathological process involved …

BACKGROUND CONTEXT: The past three decades have witnessed increasing interest in
strategies to improve neurologic function after spinal cord injury. As progress is made in our …