BACKGROUND Miscarriage is the spontaneous loss of a pregnancy before 12 weeks (early
miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs in …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Background Understanding the dynamic cellular behaviors and underlying molecular
mechanisms that drive morphogenesis is an ongoing challenge in biology. Live imaging …

The family of secreted Wingless ligands plays major roles in embryonic development, stem
cell maintenance, differentiation and tissue homeostasis. Accumulating evidence suggests …

MicroRNAs (miRNAs) act as important epigenetic posttranscriptional regulators of gene
expression. We aimed to gain more understanding of the complex gene expression …

Spatially ordered embryo-like structures self-assembled from blastocyst-derived stem cells
can be generated to mimic embryogenesis in vitro. However, the assembly system and …

STUDY QUESTION Is the composition of microRNAs (miRNAs) in uterine fluid (UF) of
women with recurrent implantation failure (RIF) different from that of healthy fertile women …

Embryonic stem cells and induced pluripotent stem (iPS) cells are characterized by their
ability to self-renew and to generate differentiated cells of all three germ layers. This …

Successful embryo implantation depends on the quality of the embryo, as well as on the
receptivity of the endometrium. The aim of this study was to investigate the endometrial gene …