Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …

Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
today. The search for new treatments is made ever more urgent by prospects for increasing …

Background Alzheimer's disease (AD) is the most common type of dementia, affecting one in
eight adults over 65 years of age. The majority of AD cases are sporadic, with unknown …

Understanding the immune compartment of tumors facilitates the development of
revolutionary new therapies. We used a Kras (G12D)-driven mouse model of lung cancer to …

Synaptic failure is an immediate cause of cognitive decline and memory dysfunction in
Alzheimer's disease. Dendritic spines are specialized structures on neuronal processes, on …

Substantial progress has been made toward understanding the neuropathology, genetic
origins, and epidemiology of neurodegenerative diseases, including Alzheimer's disease; …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized pathologically by
progressive neuronal loss, extracellular plaques containing the amyloid-β (Aβ) peptides …

The hypothesis that amyloid pathology precedes and induces the tau pathology of
Alzheimer's disease is experimentally supported here through the identification of GSK-3 …

Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic
transmission represent the principal experimental models underlying learning and memory …

Alzheimer disease (AD) is the most common form of adult dementia. Its pathological
hallmarks are synaptic degeneration, deposition of amyloid plaques and neurofibrillary …