The main indication for the transfusion of plasma is to correct deficiencies of clotting factors,
for which a specific concentrate is not available, in patients with active bleeding. The …

Purpose To review the pathophysiology of coagulopathy in massively transfused, adult and
previously hemostatically competent patients in both elective surgical and trauma settings …

Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …

We simulate the cross-flow migration of rigid particles such as platelets in a red blood cell
(RBC) suspension using the Stokes flow boundary integral equation method. Two types of …

The transfusion of red cell concentrates (RCC) is indicated in order to achieve a fast
increase in the supply of oxygen to the tissues, when the concentration of haemoglobin (Hb) …

BACKGROUND: Preoperative bleeding time (BT) does not correlate with postoperative
bleeding in patients subjected to surgical procedures. A significant positive correlation has …

Postpartum hemorrhage (PPH) is one of the top 5 causes of maternal mortality in developed
and developing countries. The incidence of PPH is 40% after vaginal delivery and 30% after …

Haemorrhage remains a major cause of potentially preventable deaths. Trauma and
massive transfusion are associated with coagulopathy secondary to tissue injury …

Trauma-induced coagulopathy is caused by multiple factors, such as anemia, hemodilution,
hypothermia, acidosis, shock, and serious trauma itself, which affects patient outcomes due …

Massive haemorrhage is common and often associated with high morbidity and mortality.
We perform a systematic review of the literature, with extraction of the recommendations …