Tramadol—an atypical opioid analgesic—has a unique pharmacokinetic and
pharmacodynamic profile, with opioidergic, noradrenergic, and serotonergic actions …

In this review we describe the evidence base for postoperative analgesia after maxillofacial
surgery. We discuss the implications of poorly managed pain, risk factors for the …

Purpose In this prospective, randomized, double-blind, controlled study, we evaluated the
effects of leukocyte-and platelet-rich fibrin (L-PRF) alone and combined with hyaluronic acid …

Purpose In this prospective, randomized, double-blind controlled study, we evaluated the
effects of leukocyte-and platelet-rich fibrin (L-PRF) alone and combined with a hyaluronic …

Aim: This study compared the analgesic efficacy of intra socket application of tramadol
versus ketamine for preventing pain after mandibular third molar surgery. Materials and …

Tramadol is an analgesic usually prescribed for the management of pain, with a certain risk
of addiction in chronic patients. The incorporation of tramadol in sustained-release systems …

Aim Pain control is an important aspect of ED patient management, and there are many
different protocols used around the world influenced by both availability of local resources …

Morphine and tramadol are the opioid analgesic drugs acting via activation of μ‑opioid
receptors. It is important to understand which mechanism (synergistic or additive anti …

The goal of the present study was to evaluate the efficacy of topical tramadol in the
management of knee osteoarthritis pain. Sixty patients with moderate to severe pain of knee …

Purpose Evidence exists to support the peripheral analgesic effect of local administration of
ketamine (LAK) after third molar surgery. The aim of the present systematic review and meta …