Melanocytic nevi and melanoma: unraveling a complex relationship
WE Damsky, M Bosenberg - Oncogene, 2017 - nature.com
Approximately 33% of melanomas are derived directly from benign, melanocytic nevi.
Despite this, the vast majority of melanocytic nevi, which typically form as a result of BRAF …
Despite this, the vast majority of melanocytic nevi, which typically form as a result of BRAF …
[HTML][HTML] Update in genetic susceptibility in melanoma
M Potrony, C Badenas, P Aguilera… - Annals of …, 2015 - ncbi.nlm.nih.gov
Melanoma is the most deadly of the common skin cancers and its incidence is rapidly
increasing. Approximately 10% of cases occur in a familial context. To date, cyclin …
increasing. Approximately 10% of cases occur in a familial context. To date, cyclin …
Age-specific incidence of melanoma in the United States
Importance Melanoma is epidemiologically linked to UV exposure, particularly childhood
sunburn. Public health campaigns are increasing sun-protective behavior in the United …
sunburn. Public health campaigns are increasing sun-protective behavior in the United …
Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy
Histopathological evaluation of melanocytic tumours usually allows reliable distinction of
benign melanocytic naevi from melanoma. More difficult is the histopathological …
benign melanocytic naevi from melanoma. More difficult is the histopathological …
Melanoma: a global perspective
Most of our current knowledge of melanoma is derived from the study of patients from
populations of European descent, for whom public health, sun protection initiatives and …
populations of European descent, for whom public health, sun protection initiatives and …
[HTML][HTML] Familial melanoma and susceptibility genes: a review of the most common clinical and dermoscopic phenotypic aspect, associated malignancies and …
L Zocchi, A Lontano, M Merli, E Dika, E Nagore… - Journal of clinical …, 2021 - mdpi.com
A family history of melanoma greatly increases the risk of developing cutaneous melanoma,
a highly aggressive skin cancer whose incidence has been steadily increasing worldwide …
a highly aggressive skin cancer whose incidence has been steadily increasing worldwide …
[HTML][HTML] Familial melanoma: diagnostic and management implications
M Rossi, C Pellegrini, L Cardelli… - … practical & conceptual, 2019 - ncbi.nlm.nih.gov
Background An estimated 5%–10% of all cutaneous melanoma cases occur in families. This
review describes susceptibility genes currently known to be involved in melanoma …
review describes susceptibility genes currently known to be involved in melanoma …
[HTML][HTML] Detection of exosomal miRNAs in the plasma of melanoma patients
SR Pfeffer, KF Grossmann, PB Cassidy… - Journal of clinical …, 2015 - mdpi.com
MicroRNAs (miRNAs) are a class of 22–25 nucleotide RNAs that control gene expression at
the post-transcriptional level. MiRNAs have potential as cancer biomarkers. Melanoma is a …
the post-transcriptional level. MiRNAs have potential as cancer biomarkers. Melanoma is a …
[HTML][HTML] Current molecular markers of melanoma and treatment targets
Melanoma is a deadly skin cancer that becomes especially difficult to treat after it
metastasizes. Timely identification of melanoma is critical for effective therapy, but …
metastasizes. Timely identification of melanoma is critical for effective therapy, but …
Focus on cutaneous and uveal melanoma specificities
C Pandiani, GE Béranger, J Leclerc… - Genes & …, 2017 - genesdev.cshlp.org
Cutaneous melanoma (CM) and uveal melanoma (UM) derive from cutaneous and uveal
melanocytes that share the same embryonic origin and display the same cellular function …
melanocytes that share the same embryonic origin and display the same cellular function …