A review of the pharmacological activities and recent synthetic advances of γ-butyrolactones

J Hur, J Jang, J Sim - International Journal of Molecular Sciences, 2021 - mdpi.com
γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of
diverse natural products and biologically active small molecules. Because of their broad …

Combining activity profiling with advanced annotation to accelerate the discovery of natural products targeting oncogenic signaling in melanoma

T Hell, A Rutz, L Dürr, M Dobrzyński… - Journal of natural …, 2022 - ACS Publications
The discovery of bioactive natural products remains a time-consuming and challenging task.
The ability to link high-confidence metabolite annotations in crude extracts with activity …

Anti-inflammatory role of Artemisia argyi methanol extract by targeting the caspase-11 non-canonical inflammasome in macrophages

YB Kim, HJ Cho, YS Yi - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Artemisia argyi possesses pharmacological activities
against various immunopathological conditions associated with inflammation. Aim of the …

[HTML][HTML] New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity

L Su, X Zhang, Y Ma, C Geng, X Huang, J Hu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Leading by cytotoxicity against HepG2 cells, bioactivity-guided fractionation of the EtOAc
fraction from Artemisia atrovirens led to the isolation of 18 new guaianolide dimers …

Gastroprotective effect of eupatilin, a polymethoxyflavone from Artemisia argyi H. Lév. & Vaniot, in ethanol-induced gastric mucosal injury via NF-κB signaling pathway

K Du, C Zheng, Z Kuang, Y Sun, Y Wang, S Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Artemisia argyi H. Lév. & Vaniot (AA) has been extensively
utilized as an important medicine and food homology in China, Japan, Korea, and eastern …

The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids

L Flores-Bocanegra, HA Raja, TN Graf… - Journal of natural …, 2020 - ACS Publications
Two separate commercial products of kratom [Mitragyna speciosa (Korth.) Havil. Rubiaceae]
were used to generate reference standards of its indole and oxindole alkaloids. While …

Artematrovirenolides A—D and Artematrolides S—Z, Sesquiterpenoid Dimers with Cytotoxicity against Three Hepatoma Cell Lines from Artemisia atrovirens

LH Su, TZ Li, YB Ma, CA Geng… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Inspired by the intriguing structures and remarkable activities of
sesquiterpenoid dimers, 12 new sesquiterpenoid dimers, artematrovirenolides A—D (1—4) …

Immunosuppressive Activity of Artemisia argyi Extract and Isolated Compounds

AM Zimmermann-Klemd, JK Reinhardt… - Frontiers in …, 2020 - frontiersin.org
The need for novel drugs for the treatment of autoimmune diseases is high, since available
pharmaceuticals often have substantial side effects and limited efficacy. Natural products are …

Computational methods and points for attention in absolute configuration determination

H Zhu, Y Wang, LA Nafie - Frontiers in Natural Products, 2023 - frontiersin.org
With the rapid development of high performance computers and computational methods,
including software, an increasing number of experimental chemists have tried to use …

Anti-inflammatory sesquiterpenoid dimers from Artemisia atrovirens

Z Shao, L Li, Y Zheng, Q Gong, CQ Ke, S Yao, H Zhang… - Fitoterapia, 2022 - Elsevier
Eight new sesquiterpenoid dimers, artatrovirenolides AH (1–8), along with three known
analogues (9–11), were isolated from Artemisia atrovirens by using the LC-MS guided …