Curcumin and its derivatives as potential antimalarial and anti-inflammatory agents: a review on structure–activity relationship and mechanism of action

SNH Jamil, AH Ali, SR Feroz, SD Lam, HK Agustar… - Pharmaceuticals, 2023 - mdpi.com
Curcumin, one of the major ingredients of turmeric (Curcuma longa), has been widely
reported for its diverse bioactivities, including against malaria and inflammatory-related …

Stoichiometric and Catalytic C−C and C−H Bond Formation with B(C6F5)3 via Cationic Intermediates

Y Soltani, LC Wilkins, RL Melen - … Chemie International Edition, 2017 - Wiley Online Library
This work showcases a new catalytic cyclization reaction using a highly Lewis acidic borane
with concomitant C− H or C− C bond formation. The activation of alkyne‐containing …

New insight-guided approaches to detect, cure, prevent and eliminate malaria

S Kumar, R Kumari, R Pandey - Protoplasma, 2015 - Springer
New challenges posed by the development of resistance against artemisinin-based
combination therapies (ACTs) as well as previous first-line therapies, and the continuing …

[HTML][HTML] Molecular modelling, synthesis, and antimalarial potentials of curcumin analogues containing heterocyclic ring

SN Balaji, MJ Ahsan, SS Jadav, V Trivedi - Arabian Journal of Chemistry, 2019 - Elsevier
The molecular modelling approach was applied to a series of nineteen curcumin analogues
to find the possible PfRIO2 kinase inhibitory action. A putative active site in flexible loop (S1) …

Isolation and quantification of antimalarial N-alkylamides from flower-head derived in vitro callus cultures of Spilanthes paniculata

R Rajendran, BS Narashimman, V Trivedi… - Journal of bioscience …, 2017 - Elsevier
This is the pioneer work reporting on simple procedure for synchronized determination and
quantification of two biologically active N-alkylamides,(2E, 6Z, 8E)-N-isobutyl-2, 6, 8 …

Discovery of anti-malarial agents through application of in silico studies

M A. Barmade, P R. Murumkar… - … Chemistry & High …, 2015 - benthamdirect.com
Among the various parasitic diseases, malaria is the deadliest one. Due to the emergence of
high drug resistance to the existing drug candidates there is a global need for development …

Stöchiometrische und katalytische C‐C‐und C‐H‐Bindungsbildung mit B (C6F5) 3 über kationische Zwischenstufen

Y Soltani, LC Wilkins, RL Melen - Angewandte Chemie, 2017 - Wiley Online Library
Diese Arbeit beschreibt eine neuartige katalytische Cyclisierung unter Verwendung eines
stark Lewis‐sauren Borans mit einhergehender C‐H‐oder C‐C‐Bindungsbildung. Die …

New possibilities of 2-pyranone derivatives–Thermal, optical and electrochemical properties

S Kula, A Szlapa-Kula, S Krompiec… - Materials Science and …, 2021 - Elsevier
The paper contains a comprehensive study regarding the new possibilities of using 2-
pyranone derivatives. In this work, six compounds of this type (including three …

[PDF][PDF] Molecular beacon probe based promoter motifs validation in anoxia responsive differentially expressed genes and their in silico interaction studies with AP2 …

GK Prajapati, DM Pandey - Int J Pharm Pharm Sci, 2015 - researchgate.net
Objective: Progressive evolution in molecular biology revealed the differential expression of
genes and their regulatory mechanism in rice under anoxia. In addition to that the …

Identifizierung neuer antiplasmodialer Wirkstoffe und Validierung von PfGSK3 als potentiellen Medikamentenangriffspunkt gegen Malaria

A Alder - 2020 - ediss.sub.uni-hamburg.de
Mit über 228 Mio. Infektionen im Jahr 2018, von denen ca. 405 000 tödlich verliefen, ist
Malaria eine der bedeutendsten Infektionskrankheiten der Welt. Verursacht wird die …