[HTML][HTML] Geometric construction of viral genome space and its applications

N Sun, S Pei, L He, C Yin, RL He, SST Yau - Computational and Structural …, 2021 - Elsevier
Understanding the relationships between genomic sequences is essential to the
classification and characterization of living beings. The classes and characteristics of an …

Multi-objective optimization-based workflow scheduling for applications with data locality and deadline constraints in geo-distributed clouds

D Wu, X Wang, X Wang, M Huang, R Zeng… - Future Generation …, 2024 - Elsevier
Geo-distributed clouds have emerged as a new generation of cloud computing paradigm, in
which each cloud is operated and managed by independent cloud service providers (CSPs) …

[HTML][HTML] Determination of the nucleotide or amino acid composition of genome or protein sequences by using natural vector method and convex hull principle

X Jiao, S Pei, Z Sun, J Kang, SST Yau - Fundamental Research, 2021 - Elsevier
Although with the continuous development of sequencing technology, the number of
genome and protein sequences has grown rapidly, these sequences are only a small part of …

An efficient numerical representation of genome sequence: natural vector with covariance component

N Sun, X Zhao, SST Yau - PeerJ, 2022 - peerj.com
Background The characterization and comparison of microbial sequences, including
archaea, bacteria, viruses and fungi, are very important to understand their evolutionary …

Grand Biological Universe: Genome space geometry unravels looking for a single metric is likely to be futile in evolution

N Sun, H Yu, R Ren, T Zhou, M Guan, L Zhao, SST Yau - bioRxiv, 2023 - biorxiv.org
Understanding the differences between genomic sequences of different lives is crucial for
biological classification and phylogeny. Here, we downloaded all the reliable sequences of …

[图书][B] Mathematical Principles in Bioinformatics

SST Yau, X Zhao, K Tian, H Yu - 2024 - books.google.com
This textbook introduces bioinformatics to students in mathematics with no biology
background assumed and it provides solid mathematical tools for biology students along …

Globally Solving Concave Quadratic Program via Doubly Nonnegative Relaxation

Z Qu, T Zeng, Y Lou - arXiv preprint arXiv:2302.05930, 2023 - arxiv.org
We consider the problem of maximizing a convex quadratic function over a bounded
polyhedral set. We design a new framework based on SDP relaxation and cutting plane …

Convex Hull Principle and Distinguishing Proteins from Arbitrary Amino Acid Sequences

SST Yau, X Zhao, K Tian, H Yu - Mathematical Principles in Bioinformatics, 2023 - Springer
In every natural science field, it is important to discover the laws that govern it. In chemistry,
there are three laws: the Law of Mass Conservation, the Law of Definite Proportions, and the …

SARS-Cov-2 variants: biological and mathematical considerations for nomenclature

J Huang, Y Mi, J Li, GR McLean - Medical Research …, 2022 - repository.londonmet.ac.uk
Coronavirus (CoV) is one of the most widely used words during the past two years. If it were
announced that Delta CoV only affects animals such as pigs and wigeons while Omicron …

Mathematical Principles in Bioinformatics

STY Stephen, X Zhao, K Tian, H Yu - Springer
Bioinformatics is among the newest and most highly demanded subjects in biology and
mathematics. In recent years, however, bioinformatics has undergone vast changes in style …