A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …

Background & Objective: Traumatic Brain Injury (TBI) is one of the major causes of mortality
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …

Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …

Background: Traumatic brain injury (TBI) constitutes the primary reason for mortality and
morbidity in persons worldwide below 45 years of age. 1.7 million Traumatic events occur …

Introduction: Adverse immune activation contributes to many central nervous system (CNS)
disorders. All main CNS cell types express toll-like receptor 4 (TLR 4). This receptor is …

Traumatic brain injury (TBI) is seen by the insurance industry and many health care
providers as an “event.” Once treated and provided with a brief period of rehabilitation, the …

Clinical evidence has established that concomitant traumatic brain injury (TBI) accelerates
bone healing, but the underlying mechanism is unclear. This study shows that after TBI …

Tanshinones, lipophilic diterpenes isolated from the rhizome of Salvia miltiorrhiza, have
diverse pharmacological activities against human ailments including neurological diseases …

Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …

The knowledge of the pathophysiology after traumatic head injury is necessary for adequate
and patient-oriented treatment. As the primary insult, which represents the direct mechanical …