Following periods of haematopoietic cell stress, such as after chemotherapy, radiotherapy,
infection and transplantation, patient outcomes are linked to the degree of immune …

Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

Epidemiological data suggest that early life exposures are key determinants of immune-
mediated disease later in life. Young children are also particularly susceptible to infections …

Advances in single-cell mass cytometry have increasingly improved highly multidimensional
characterization of immune cell heterogeneity. The immunoassay multiplexing capacity …

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the most effective
treatment for selected patients with acute myeloid leukemia (AML) and relies on a “graft …

Single-cell analysis provides insights into cellular heterogeneity and dynamics of individual
cells. This Feature highlights recent developments in key analytical techniques suited for …

The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to
gain mechanistic insight and identify predictive signatures for personalization. However …

There are fundamental differences between humans and the animals we typically use to
study the immune system. We have learned much from genetically manipulated and inbred …

Purpose of review The ripples of artificial intelligence are being felt in various sectors of
human life. Machine learning, a subset of artificial intelligence, extracts information from …

Person-to-person transmission of SARS-CoV-2 virus has triggered a global emergency
because of its potential to cause life-threatening Covid-19 disease. By comparison to …