Mechanistic insights of formulation approaches for the treatment of nail infection: conventional and novel drug delivery approaches
Onychomycosis is a chronic disorder that is difficult to manage and hard to eradicate with
perilous trends to relapse. Due to increased prevalence of HIV, use of immunosuppressant …
perilous trends to relapse. Due to increased prevalence of HIV, use of immunosuppressant …
Iontophoresis to overcome the challenge of nail permeation: considerations and optimizations for successful ungual drug delivery
K Chen, V Puri, B Michniak-Kohn - The AAPS journal, 2021 - Springer
Iontophoresis is a widely used drug delivery technique that has been used clinically to
improve permeation through the skin for drugs and other actives in topical formulations. It is …
improve permeation through the skin for drugs and other actives in topical formulations. It is …
Formulation-by-design of efinaconazole spanlastic nanovesicles for transungual delivery using statistical risk management and multivariate analytical techniques
As regulatory and technical landscapes for pharmaceutical formulation development are
rapidly evolving, a risk-management approach using multivariate analysis is highly essential …
rapidly evolving, a risk-management approach using multivariate analysis is highly essential …
Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design and In Vitro …
Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs
through the thick multi-layered keratinized nail plate. The objective of this investigation was …
through the thick multi-layered keratinized nail plate. The objective of this investigation was …
Iontophoresis application for drug delivery in high resistivity membranes: nails and teeth
JF Martins Andrade, T da Cunha Miranda… - Drug Delivery and …, 2023 - Springer
Iontophoresis has been vastly explored to improve drug permeation, mainly for transdermal
delivery. Despite the skin's electrical resistance and barrier properties, it has a relatively high …
delivery. Despite the skin's electrical resistance and barrier properties, it has a relatively high …
Iontophoresis for drug delivery into the nail apparatus: exploring hyponychium as the site of delivery
A Kushwaha, HN Shivakumar… - Drug development and …, 2016 - Taylor & Francis
In present studies, a hyponychium pathway (from ventral side of the nail plate) was
investigated as a potential route of drug delivery into the nail apparatus using iontophoresis …
investigated as a potential route of drug delivery into the nail apparatus using iontophoresis …
Skin uptake and clearance of ciclopirox following topical application
The assessment of skin uptake and clearance are important to determine the efficiency and
systemic safety of dermatological formulations. The objective of this study was to assess the …
systemic safety of dermatological formulations. The objective of this study was to assess the …
[图书][B] Transport of charged and uncharged solutes in hydrated human nail plate
SM Baswan - 2014 - search.proquest.com
The presence of fungal nail infections such as onychomycosis severely alters nail function
and impacts the quality of life. Topical antifungal delivery via iontophoresis is an effective …
and impacts the quality of life. Topical antifungal delivery via iontophoresis is an effective …
[PDF][PDF] Constant voltage iontophoresis technique to deliver terbinafine via Transungual delivery system: formulation optimization using box-Behnken design and In …
Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs
through the thick multi-layered keratinized nail plate. The objective of this investigation was …
through the thick multi-layered keratinized nail plate. The objective of this investigation was …