Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …
threatening systemic infections world-wide each year in severely immunocompromised …
Mitogen-activated protein kinase pathways and fungal pathogenesis
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …
The metabolic basis of Candida albicans morphogenesis and quorum sensing
TL Han, RD Cannon, SG Villas-Bôas - Fungal Genetics and Biology, 2011 - Elsevier
Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …
yeast and filamentous forms. The morphological transition appears to be a critical virulence …
Stress Response and Pathogenicity of the Necrotrophic Fungal Pathogen Alternaria alternata
KR Chung - Scientifica, 2012 - Wiley Online Library
The production of host‐selective toxins by the necrotrophic fungus Alternaria alternata is
essential for the pathogenesis. A. alternata infection in citrus leaves induces rapid lipid …
essential for the pathogenesis. A. alternata infection in citrus leaves induces rapid lipid …
The high osmolarity glycerol (HOG) pathway in fungi†
H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …
A Single MAPKKK Regulates the Hog1 MAPK Pathway in the Pathogenic Fungus Candida albicans
J Cheetham, DA Smith, A da Silva Dantas… - Molecular biology of …, 2007 - Am Soc Cell Biol
The Hog1 mitogen-activated protein kinase (MAPK) plays a central role in stress responses
in the human pathogen Candida albicans. Here, we have investigated the MAPK kinase …
in the human pathogen Candida albicans. Here, we have investigated the MAPK kinase …
Specialized and shared functions of the histidine kinase-and HOG1 MAP kinase-mediated signaling pathways in Alternaria alternata, a filamentous fungal pathogen of …
CH Lin, KR Chung - Fungal Genetics and Biology, 2010 - Elsevier
Signal transduction pathways are critical for the coordination of complex cellular processes
in cells. In Alternaria alternata, a necrotrophic fungal pathogen of citrus, cloning and …
in cells. In Alternaria alternata, a necrotrophic fungal pathogen of citrus, cloning and …
Stress signalling to fungal stress-activated protein kinase pathways
DA Smith, BA Morgan, J Quinn - FEMS microbiology letters, 2010 - academic.oup.com
The ability of microorganisms to survive and thrive within hostile environments depends on
rapid and robust stress responses. Stress-activated protein kinase (SAPK) pathways are …
rapid and robust stress responses. Stress-activated protein kinase (SAPK) pathways are …
The HOG1-like MAP kinase Sak1 of Botrytis cinerea is negatively regulated by the upstream histidine kinase Bos1 and is not involved in dicarboximide-and …
W Liu, P Leroux, S Fillinger - Fungal Genetics and Biology, 2008 - Elsevier
In filamentous ascomycetes, HOG-like signal transduction cascades are involved in the
resistance to hyper-osmotic conditions and to dicarboximides and phenylpyrroles. The …
resistance to hyper-osmotic conditions and to dicarboximides and phenylpyrroles. The …