Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy
F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …
able to evade the immune response and establish a very complex balance in which different …
NK cell-based immunotherapy for malignant diseases
M Cheng, Y Chen, W Xiao, R Sun, Z Tian - Cellular & molecular …, 2013 - nature.com
Natural killer (NK) cells play critical roles in host immunity against cancer. In response,
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …
Advances in NK cell therapy for brain tumors
J Fares, ZB Davis, JS Rechberger, SA Toll… - NPJ Precision …, 2023 - nature.com
Despite advances in treatment regimens that comprise surgery, chemotherapy, and
radiation, outcome of many brain tumors remains dismal, more so when they recur. The …
radiation, outcome of many brain tumors remains dismal, more so when they recur. The …
Magneto-activation and magnetic resonance imaging of natural killer cells labeled with magnetic nanocomplexes for the treatment of solid tumors
Natural killer (NK) cell-based immunotherapy has been considered a promising cell-based
cancer treatment strategy with low side effects for early tumors and metastasis. However, the …
cancer treatment strategy with low side effects for early tumors and metastasis. However, the …
[PDF][PDF] Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans
K Ishiyama, H Ohdan, M Ohira, H Mitsuta, K Arihiro… - …, 2006 - Wiley Online Library
In rodents, liver natural killer (NK) cells have been shown to mediate higher cytotoxic activity
against tumor cells than do peripheral blood (PB) NK cells. However, such differences …
against tumor cells than do peripheral blood (PB) NK cells. However, such differences …
The immunoimaging toolbox
AT Mayer, SS Gambhir - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
The recent clinical success of cancer immunotherapy has renewed interest in the
development of tools to image the immune system. In general, immunotherapies attempt to …
development of tools to image the immune system. In general, immunotherapies attempt to …
Molecular imaging of innate immunity and immunotherapy
The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …
Advances in Molecular Imaging Strategies for In Vivo Tracking of Immune Cells
HW Lee, P Gangadaran, S Kalimuthu… - BioMed research …, 2016 - Wiley Online Library
Tracking of immune cells in vivo is a crucial tool for development and optimization of cell‐
based therapy. Techniques for tracking immune cells have been applied widely for …
based therapy. Techniques for tracking immune cells have been applied widely for …
IL-2− driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell …
S Huenecke, SY Zimmermann, S Kloess… - Journal of …, 2010 - journals.lww.com
To characterize natural killer (NK) cell subpopulations during activation, we analyzed the NK
cell receptor repertoire and functionality of purified clinical scale CD56+ CD3− donor NK …
cell receptor repertoire and functionality of purified clinical scale CD56+ CD3− donor NK …
IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study
C Brehm, S Huenecke, A Quaiser, R Esser, M Bremm… - PloS one, 2011 - journals.plos.org
In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk
leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK …
leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK …