Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …

Natural killer (NK) cells play critical roles in host immunity against cancer. In response,
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …

Despite advances in treatment regimens that comprise surgery, chemotherapy, and
radiation, outcome of many brain tumors remains dismal, more so when they recur. The …

Natural killer (NK) cell-based immunotherapy has been considered a promising cell-based
cancer treatment strategy with low side effects for early tumors and metastasis. However, the …

In rodents, liver natural killer (NK) cells have been shown to mediate higher cytotoxic activity
against tumor cells than do peripheral blood (PB) NK cells. However, such differences …

The recent clinical success of cancer immunotherapy has renewed interest in the
development of tools to image the immune system. In general, immunotherapies attempt to …

The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …

Tracking of immune cells in vivo is a crucial tool for development and optimization of cell‐
based therapy. Techniques for tracking immune cells have been applied widely for …

To characterize natural killer (NK) cell subpopulations during activation, we analyzed the NK
cell receptor repertoire and functionality of purified clinical scale CD56+ CD3− donor NK …

In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk
leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK …