Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

H Zhao, T Ming, S Tang, S Ren, H Yang, M Liu, Q Tao… - Molecular cancer, 2022 - Springer
Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

Wnt pathway in bone repair and regeneration–what do we know so far

KS Houschyar, C Tapking, MR Borrelli… - Frontiers in cell and …, 2019 - frontiersin.org
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

[HTML][HTML] CircRNA_100367 regulated the radiation sensitivity of esophageal squamous cell carcinomas through miR-217/Wnt3 pathway

J Liu, N Xue, Y Guo, K Niu, L Gao, S Zhang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: Circular RNAs (circRNAs) play important roles in regulating the radioresistance
of esophageal squamous cell carcinoma (ESCC). This study aimed to determine the role of …

Deregulated miRNAs in bone health: Epigenetic roles in osteoporosis

D Bellavia, A De Luca, V Carina, V Costa, L Raimondi… - Bone, 2019 - Elsevier
MicroRNA (miRNA) has shown to enhance or inhibit cell proliferation, differentiation and
activity of different cell types in bone tissue. The discovery of miRNA actions and their targets …

The role of microRNAs in bone metabolism and disease

Y Gao, S Patil, A Qian - International journal of molecular sciences, 2020 - mdpi.com
Bone metabolism is an intricate process involving various bone cells, signaling pathways,
cytokines, hormones, growth factors, etc., and the slightest deviation can result in various …

[HTML][HTML] Contribution of miRNAs and lncRNAs in osteogenesis and related disorders

S Ghafouri-Fard, A Abak, ST Avval, S Rahmani… - Biomedicine & …, 2021 - Elsevier
Non-coding RNAs have been found to regulate several developmental processes among
them is osteogenesis. Although these transcripts have several distinct classes, two classes …

[HTML][HTML] miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN

M He, P Shen, C Qiu, J Wang - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Dysregulation of microRNA (miRNA) has been observed in several types of tumors,
including osteosarcoma. Biochip analysis was used to identify miRNAs differentially …

MiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy

S Li, L Gao, W Zhang, Y Yu, J Zheng, X Liang… - Stem Cell Research & …, 2022 - Springer
Background Osteoporosis affects the mandible resulting in bone loss. Though impairments
are not life threatening, they affect a person's quality-of-life particularly vulnerable elderly …

[HTML][HTML] miR-16-2* interferes with WNT5A to regulate osteogenesis of mesenchymal stem cells

L Duan, H Zhao, Y Xiong, X Tang, Y Yang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Osteoporosis is a bone metabolic disease characterized by a systemic
impairment of bone mass, which results in increased propensity of fragility fractures. A …

Regulatory of miRNAs in tri-lineage differentiation of C3H10T1/2

W Huang, X Wu, S Xiang, M Qiao, H Li, Y Zhu… - Stem cell research & …, 2022 - Springer
MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules encoded by
endogenous genes, which play a vital role in cell generation, metabolism, apoptosis and …