Genetic deficiencies of early components of the classical complement activation pathway
(especially C1q, r, s, and C4) are the strongest monogenic causal factors for the prototypic …

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can
potentially lead to serious organ complications and even death. Its global burden—in terms …

We performed a genome-wide association study (GWAS) of systemic lupus erythematosus
(SLE) in a Chinese Han population by genotyping 1,047 cases and 1,205 controls using …

FcγRIIB is the only inhibitory Fc receptor. It controls many aspects of immune and
inflammatory responses, and variation in the gene encoding this protein has long been …

Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks almost every
organ. The condition mostly happens to adults but is also found in children, and the latter …

Objective To examine the lifetime prevalence of mood and anxiety disorders in patients with
systemic lupus erythematosus (SLE). Demographic and disease‐related variables were …

Introduction Autoantibodies have a central role in systemic lupus erythematosus (SLE). The
presence of autoantibodies preceding disease onset by years has been reported both in …

Genome-wide association studies and fine mapping of candidate regions have rapidly
advanced our understanding of the genetic basis of systemic lupus erythematosus (SLE) …

Systemic lupus erythematosus (SLE, lupus) is a highly complex and heterogeneous
autoimmune disease that most often afflicts women in their child-bearing years. It is …

Systemic lupus erythematosus is the prototypical systemic autoimmune disease, as it is
characterized both by protean multi-organ system manifestations and by the uniform …