A review exploring therapeutic worth of 1, 3, 4-oxadiazole tailored compounds
1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …
Synthesis, physiochemical property and antimicrobial activity of novel quaternary ammonium salts
X Xie, W Cong, F Zhao, H Li, W Xin… - Journal of enzyme …, 2018 - Taylor & Francis
Abstract Twenty-four novel 5-phenyl-1, 3, 4-oxadiazole-2-thiol (POT) analogues, benzo [d]
oxazole-2-thiol, benzo [d] thiazole-2-thiol and 5-methyl-1, 3, 4-thiadiazole-2-thiol-substituted …
oxazole-2-thiol, benzo [d] thiazole-2-thiol and 5-methyl-1, 3, 4-thiadiazole-2-thiol-substituted …
[PDF][PDF] Virtual screening of piperidine based small molecules against COVID-19
COVID-19 was declared a global pandemic in March 2020. Due to urgency with less time,
there was a need to explore the potential treatment to address this severe health issue. Drug …
there was a need to explore the potential treatment to address this severe health issue. Drug …
[HTML][HTML] Synthesis, antimicrobial evaluation and hemolytic activity of 2-[[5-alkyl/aralkyl substituted-1, 3, 4-oxadiazol-2-yl] thio]-N-[4-(4-morpholinyl) phenyl] acetamide …
Disubstituted 1, 3, 4-oxadiazole compounds are one of the most attractive classes for
researchers due to their pharmacological activities. In the current research, a new series of 2 …
researchers due to their pharmacological activities. In the current research, a new series of 2 …
Synthesis of new heterocyclic 3-piperidinyl-1, 3, 4-oxadiazole derivatives as potential drug candidate for the treatment of Alzheimer's disease
A series of new N-substituted derivatives of 3-[(5-{1-[(4-chlorophenyl) sulfonyl]-3-piperidinyl}-
1, 3, 4-oxadiazol-2-yl) sulfanyl] propanamide (7a–q) was synthesized to evaluate new drug …
1, 3, 4-oxadiazol-2-yl) sulfanyl] propanamide (7a–q) was synthesized to evaluate new drug …
[HTML][HTML] Synthesis of some new 5-substituted-2-((6-chloro-3, 4-methylenedioxyphenyl) methylthio)-1, 3, 4-Oxadiazole derivatives as suitable antibacterial inhibitors
A Siddiqa, MA Abbasi, S Rasool, SZ Siddiqui… - Bulletin of Faculty of …, 2015 - Elsevier
Heterocyclic molecules belong to the most attractive group owing to their broad spectrum of
antimicrobial activities. In the undertaken research, a number of new 5-substituted-2-((6 …
antimicrobial activities. In the undertaken research, a number of new 5-substituted-2-((6 …
Multi-selective reaction of azinane bearing oxadiazoles and substituted haloalkanes catalyzed by alkali metal hydride to access anti-enzymatic agents
The diverse biological activities of 1, 3, 4-oxadiazole derivatives are very significant due to
structural complexity. Concentrating on metal free synthesis of 1, 3, 4-oxadiazole hybrids, 5a …
structural complexity. Concentrating on metal free synthesis of 1, 3, 4-oxadiazole hybrids, 5a …
HCV genotype-specific drug discovery through structure-based virtual screening
Abstract Hepatitis C Virus (HCV) poses great threat worldwide, and is a major cause for liver
cancer. HCV genome encodes polyprotein that is subsequently cleaved into independently …
cancer. HCV genome encodes polyprotein that is subsequently cleaved into independently …
Molecular modeling approach of serine protease NS3-4A genotype 3a as a potential drug target of hepatitis C virus: Homology modeling and virtual screening study
Hepatitis C Virus (HCV), affecting millions of people worldwide, is the leading cause of liver
disorder, cirrhosis, and hepatocellular carcinoma. HCV is genetically diverse having seven …
disorder, cirrhosis, and hepatocellular carcinoma. HCV is genetically diverse having seven …
[HTML][HTML] Synthesis, characterization and pharmacological evaluation of different 1, 3, 4-oxadiazole and acetamide derivatives of ethyl nipecotate
K Nafeesa, MA Abbasi, SZ Siddiqui, S Rasool… - Bulletin of Faculty of …, 2017 - Elsevier
A new series of N-substituted derivatives of 2-[(5-{1-[(4-chlorophenyl) sulfonyl]-3-piperidinyl}-
1, 3, 4-oxadiazol-2-yl) sulfanyl] acetamide (6a-w) has been designed and synthesized with …
1, 3, 4-oxadiazol-2-yl) sulfanyl] acetamide (6a-w) has been designed and synthesized with …