[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: A systematic review
D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …
affecting around 46 million people worldwide but few treatments are currently available. The …
Hearing loss and cognition: what we know and where we need to go
Although a causal association remains to be determined, epidemiologic evidence suggests
an association between hearing loss and increased risk of dementia. If we determine the …
an association between hearing loss and increased risk of dementia. If we determine the …
[HTML][HTML] Identifying health conditions associated with Alzheimer's disease up to 15 years before diagnosis: an agnostic study of French and British health records
T Nedelec, B Couvy-Duchesne, F Monnet… - The Lancet Digital …, 2022 - thelancet.com
Background The identification of modifiable risk factors for Alzheimer's disease is paramount
for early prevention and the targeting of new interventions. We aimed to assess the …
for early prevention and the targeting of new interventions. We aimed to assess the …
Hearing impairment and cognition in an aging world
With the increasing number of older adults around the world, the overall number of dementia
cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million …
cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million …
The impact and causal directions for the associations between diagnosis of ADHD, socioeconomic status, and intelligence by use of a bi-directional two-sample …
Background Previous studies have reported associations between attention-
deficit/hyperactivity disorder (ADHD) and lower socioeconomic status and intelligence. We …
deficit/hyperactivity disorder (ADHD) and lower socioeconomic status and intelligence. We …
Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity
GD Carrasquilla, M García-Ureña, T Fall, TIA Sørensen… - Elife, 2022 - elifesciences.org
Physical inactivity and increased sedentary time are associated with excess weight gain in
observational studies. However, some longitudinal studies indicate reverse causality where …
observational studies. However, some longitudinal studies indicate reverse causality where …
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci
BL Mitchell, JR Saklatvala, N Dand… - Nature …, 2022 - nature.com
Acne vulgaris is a highly heritable skin disorder that primarily impacts facial skin. Severely
inflamed lesions may leave permanent scars that have been associated with long-term …
inflamed lesions may leave permanent scars that have been associated with long-term …
Variability in cochlear implantation outcomes in a large German cohort with a genetic etiology of hearing loss
A Tropitzsch, T Schade-Mann, P Gamerdinger… - Ear and …, 2023 - journals.lww.com
Objectives: The variability in outcomes of cochlear implantation is largely unexplained, and
clinical factors are not sufficient for predicting performance. Genetic factors have been …
clinical factors are not sufficient for predicting performance. Genetic factors have been …
Dementia prevention in clinical practice
K Niotis, K Akiyoshi, C Carlton… - Seminars in …, 2022 - thieme-connect.com
Over 55 million people globally are living with dementia and, by 2050, this number is
projected to increase to 131 million. This poses immeasurable challenges for patients and …
projected to increase to 131 million. This poses immeasurable challenges for patients and …
Effect of hearing aids on cognitive functions in middle-aged and older adults with hearing loss: a systematic review and meta-analysis
Z Yang, J Ni, Y Teng, M Su, M Wei, T Li… - Frontiers in Aging …, 2022 - frontiersin.org
Objective The study aimed to examine the effects of hearing aids on cognitive function in
middle-aged and older adults with hearing loss. Data sources and study selection PubMed …
middle-aged and older adults with hearing loss. Data sources and study selection PubMed …